The Human Upgrade: Biohacking for Longevity & Performance
For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.
You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.
Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.
Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.
- Update frequency
- every 3 days
- Average duration
- 57 minutes
- Episodes
- 1380
- Years Active
- 2011 - 2025
Ayurveda Meets Biohacking: 5000-Year-Old Medicine Secrets for Modern Stress | Mona Sharma : 1284
Host Dave Asprey sits down with Mona Sharma to explore how 5,000-year-old Ayurvedic practices are being used to heal stress, rewire the nervous system, and optimize modern human performance.
00:59:11 |
Thu 22 May 2025
The Biohacker’s Guide to CIA Mind Control & Brainwashing : 1283
Dave Asprey and Harvard historian Rebecca Lemov reveal how CIA mind control experiments evolved into modern psychological manipulation—and how to break free using biohacking and mental resilience.
01:03:44 |
Tue 20 May 2025
Military Tech Goes Public: Think 30% Faster with This Brain Hack | Geoffrey Woo : 1282
Discover the brain hack once reserved for Special Forces that boosts reaction time by 30%, sharpens focus, and fuels high-performance thinking—now available to the public.
01:26:32 |
Fri 16 May 2025
The Anti-Aging Chamber That Rewinds Your Biological Clock|Dr. Jason Sonners : 1281
Dave Asprey and Dr. Jason Sonners reveal how hyperbaric oxygen therapy rewires your biology, boosts stem cells, and unlocks next-level performance, recovery, and longevity.
00:49:05 |
Thu 15 May 2025
The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon : 1280
Dave Asprey and Matt Zemon reveal how psychedelic mushrooms unlock flow states, rewire the brain, and challenge everything we’ve been told about healing, addiction, and consciousness.
01:11:03 |
Tue 13 May 2025
Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah : 1279
This episode reveals how oral testosterone is transforming health, energy, and longevity for both men and women—and why diet, sleep, and willpower aren’t enough to fix the global hormone crisis.
01:05:01 |
Fri 09 May 2025
The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD : 1278
Dr. Aly Cohen reveals how hidden environmental toxins—from plastics to pesticides—disrupt hormones, damage the brain, and accelerate aging, plus actionable strategies to detox your daily life.
01:12:45 |
Thu 08 May 2025
Biohacking Your Heart Health: The Life-Saving Molecule You NEED to Know | Dr. Anurag Singh : 1277
Dave Asprey and Dr. Anurag Singh reveal how boosting mitochondrial function with Urolithin A can reverse heart aging, enhance energy, and protect against disease.
01:04:18 |
Tue 06 May 2025
How Laser Therapy Boosts Mood, Mental Clarity, and Consciousness with Dr. Brandon Crawford : 1276
Dr. Brandon Crawford joins Dave Asprey to reveal how advanced laser therapy is rewiring the brain, restoring lost function, and unlocking higher states of consciousness through precision light modula…
00:40:48 |
Thu 01 May 2025
Conscious Bacteria? The Secret New Science of Cellular Intelligence | Zach Bush : 1275
Dave Asprey and Zach Bush, MD, reveal how restoring mitochondrial intelligence, microbiome health, and cellular communication unlocks true healing, resilience, and human evolution.
01:42:47 |
Tue 29 Apr 2025
The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle : 1275
Discover how REHIT—Reduced Exertion High-Intensity Training—outperforms traditional cardio in boosting VO2 max, insulin sensitivity, and brain function in under 10 minutes per week.
01:06:22 |
Fri 25 Apr 2025
The Real Reason You Still Feel Tired—Even When Your Bloodwork Looks Perfect | Dr Pompa : 1273
Discover why feeling sick with “perfect” bloodwork isn’t in your head—and how fixing cellular function, not chasing symptoms, holds the key to real healing.
01:18:47 |
Thu 24 Apr 2025
The $500 Billion Secret: Why Top Leaders Chase Stress | Sébastien Page : 1272
A $500 billion fund manager reveals how stress, procrastination, and emotional pressure—when used strategically—can unlock peak performance, resilience, and better decision-making in every part of li…
01:20:27 |
Tue 22 Apr 2025
Web3 & the Future of Genetics: AI, Blockchain & Data Ownership with Nillion : 1271
A powerful conversation with two elite hacker-founders revealing how Web3, encrypted computing, and decentralized biology are giving people control over their DNA, data, and digital destiny.
01:30:03 |
Thu 17 Apr 2025
Dr. Steven Gundry: Is Fungus Secretly Running the World—and Your Gut? : 1270
Your gut may be controlling your thoughts—Dr. Steven Gundry and Dave Asprey reveal how the microbiome drives addiction, mood, and behavior in this mind-altering episode.
00:54:11 |
Tue 15 Apr 2025
Longevity Scientists Discover a Breakthrough Peptide That Reverses Hair Loss | Carolina Reis Oliveira : 1269
A team of longevity scientists led by Carolina Reis Oliveira unveils a groundbreaking peptide that targets senescent cells to reverse hair loss, restore scalp health, and transform the future of hair…
00:59:55 |
Fri 11 Apr 2025
Identity Hacker: How to Completely Change Your Personality at ANY Age | Olga Khazan : 1268
Dave Asprey and journalist Olga Khazan break down the science and strategy of changing your personality—on purpose—for better health, happiness, and success.
01:06:13 |
Thu 10 Apr 2025
Psychedelic States On-Demand (No Substances Needed) | Dr. Patrick Porter : 1267
This episode reveals how light and sound can rewire your brain, unlock psychedelic states, and boost cognition—no drugs, just pure frequency and neuroscience.
00:29:07 |
Tue 08 Apr 2025
Why Gen Z Can’t Handle the Real World (and How We Can Help Them) | Jennifer Cohen : 1266
Jennifer Cohen joins Dave Asprey to reveal how modern parenting, overprotection, and coddle culture are creating a fragile generation—and what we can do to build real resilience.
00:51:24 |
Thu 03 Apr 2025
The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld : 1265
Dave Asprey and Hannah Kleinfeld dive deep into how restoring your gut microbiome with clinically-backed probiotics can reverse brain fog, repair damage from antibiotics and GLP-1 drugs, and potentia…
01:13:03 |
Tue 01 Apr 2025
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