Authentic Biochemistry
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
- Update frequency
- every day
- Average duration
- 37 minutes
- Episodes
- 998
- Years Active
- 2019 - 2025
Porphyria gingivalis derived dihydroceramides and serine dipeptide lipids secretion induce periodontitis and systemic hyperinflammation as associated with obesity and high sucrose diet. DJGPhD.16.1.22
References
Infect Immun. 2018 Jul; 86(7): e00035-18
J Biol Chem. 2019 Jun 7;294(23):9213-9224
Egyptian Journal of Basic and Applied Sciences. 2018. (5) 4 : 237-244
Arteriosclerosis, Thrombosis, and V…
Dihydroceramides as virulence factors in periodontal disease. Dr. Daniel J. Guerra Authentic Biochemistry. 15 January 2022
References
Oral Microbiol Immunol. 2006 April 21 (2):84-92 1647-6017
Infect Immun. 2018 Jul; 86(7): e00035-18
Pathogenesis and Virulence are Linked to Alterations in the Infection Court via Secretion of Bacteriocins in Dental Plaque-producing Caries and S. pneumoniae Migration to the Lower Respiratory Tract.
References
J Dent Res. 2019 Nov;98(12):1315-1323
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1996.Vol. 335, No. 1, November 1, pp. 102–108,.
Nature Reviews Microbiology. 2003. volume 1, pages219–230
Fro…
Acquired Molecular Evolution of Antibacterial Resistance Unintentionally Selected via Pharmacotherapy to Counteract Natural Avirulence. DJGPhD. Authentic Biochemistry. 12.Jan2022
References
Infect Immun. 2013 Dec; 81(12): 4478–4489
Journal of Molecular Evolution 2020. 88:26–40
PLoS One. 2016; 11(11): e0166656
Avirulence protein factor heterogeneity in multiple mammalian host/pathogen interactions. Dr. Dan Guerra. Authentic Biochemistry Production.11.Jan.2022
References
International Journal of Pharmacy and Pharmaceutical Sciences 2015 7(9):20-29
PLoS One. 2016; 11(11): e0166656.
PLoS Pathog. 2019 Nov15;15(11):e1007687
Clin Microbiol Rev. 2006 Oct;19(4):7…
Avirulence in the Streptococci and the Two-Component System of Histidine Kinase and Response Regulator. II. DJGPhD. Authentic Biochemistry 09Jan2022
References
Front. Microbiol., 14 July 2021
PLoS One. 2016; 11(11): e0166656.
The Lancet Microbe 2021; 2(7) Pages e291-e299
Avirulence and the mechanisms of pathobiochemistry I. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production. 08.Jan 2022
Reference
Front. Microbiol., 14 July 2021
The neuronal porosomal and synaptosomal structural anatomy as a product of membrane lipid vesicular trafficking, Dr. Daniel J. Guerra Authentic Biochemistry. 05 January 2022
PLoS One. 2015 Jan 21;10(1):e0116919.
Neurochem Res. 2015 Jan;40(1):59-69
Physiology. 2009. Volume 24 Issue 6: 367-376
The bioenergetic glucose sensing network of the appetitive reward pathway is linked to the periphery via the neuroendocrine system. DJGPhD. Authentic Biochemistry. 04.Jan.2022
The human neuroendocrine system is directly regulated and in communication with the autonomic nervous system via cortical and diencephalonomic CNS nuclei. These converging networks coordinate satiet…
The Motor Neuron Association to Reward Pathway: Motor Neuron Disease , an Introduction. Dr. Daniel J. Guerra. 03 January 2022. Authentic Biochemistry Productions.
Introduction to motor neuron structure/function relationships and the MND's including Amyotrophic Lateral Sclerosis.
The CNS and Pandemic Obesity: The Appetitive Reward Pathway, Energy Expenditure, and Neuroendocrine Signaling. DJGPhD. 02.Jan.2022 Authentic Biochemistry Productions.
The CNS processes nutritional (biochemical) signaling from the external and internal environment during and subsequent to dietary ingestion. During the initiation phase, affective (limbic) and exec…
A short Pharmacology lecture on New Year's Day 2022. Dr Daniel J. Guerra. Authentic Biochemistry
Pharmacokinetics are discussed.
Appetitive Reward Pathway III.-Neurobiochemistry and Epigenetics of Addiction. DJGPhD. 31.12.21 Authentic Biochemistry
Dopaminenergic pathways are corrupted by addictive behaviors especially the use/abuse of psychoactive drugs that may become behavioral reward saliencies linked to epigenomic modifications.
Anhedonic and MDD- Associated Appetitive Reward Pathway Biochemistry and Pathophysiology II. DJGPhD. Authentic Biochemistry.30..12.21.
References
Front Neurosci. 2019; 13: 707
Nature Metabolism 2019. 1:754–764
Int. J. Mol. Sci. 2019, 20(6), 1505
Neuropsychiatr Dis Treat. 2015; 11: 875–888
Mol Psychiatry. 2016 Oct; 21(10): 1358–136…
Appetitive Reward Pathway Biochemistry and Neural Circuitry Regulation I. Dr. Daniel J. Guerra. 29.12.21. An Authentic Biochemistry Production.
References
Biol Psychiatry. 2020 Jan 1; 87(1): 64–73
Front. Neurosci., 26 November 2019
AMPK and Immuno-Epigenetic Biochemistry Part 2/2/ DJGPhD. Authentic Biochemistry 27.12.21
J Neuroinflammation. 2019; 16: 34
Nature Cell Biology, 02 Sep 2011, 13(9):1016-1023
Critical Reviews in Clinical Laboratory Sciences Volume 56, 2019 - Issue 7 Pages 472-492
AMPK and Immuno-Epigenetic Biochemistry Part 1. Dr. Daniel J. Guerra. 27.12.21. Authentic Biochemistry
References
Nat Cell Biol. 2019 Mar; 21(3): 397–407
CELL Volume 126, Issue 3, 11 August 2006, Pages 503-514
Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55
Int J Biol Sci. 2015; 11(11): 12…
AMPK negatively regulates lipogenesis by phosphorylating ACCase 1&2 plus HMGCoA reductase thus supporting beta oxidation of fatty acids . Dr. Daniel J. Guerra. 22.12.21. Authentic Biochemistry
Cell Metabolism 2020 31472-492
Amino Acids. 2012 Oct;43(4):1803-7
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690
AMPK is associated with the POMC vs, NPY neuronal axis under Leptin Control. DJGPhD. 20.12.21 Authentic Biochemistry
References
HORMONES 2013, 12(2):172-191
Proc Natl Acad Sci U S A . 2002 Dec 24;99(26):17155-60
Eur J Endocrinol. 2017 176(5): R235–R246.
AMPK Allosteric Regulation and Interaction with the Opposing mTORC Network. Part 2. Dr. Daniel J. Guerra. Authentic Biochemistry 19.12.21
Eur J Endocrinol. 2017 176(5): R235–R246
Molecular Cell Volume 81, Issue 18, 16 September 2021, Pages 3677-3690