Authentic Biochemistry
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
- Update frequency
- every day
- Average duration
- 37 minutes
- Episodes
- 996
- Years Active
- 2019 - 2025
Dr. Guerra provides a clinical discussion of HCC pathogenesis and treatment including the role of HCV. 03 July 2019
Dr Guerra of Authentic Biochemistry navigates through the protease inhibitor literature and starts a journey into hepatitis C virus (HCV)-mediated HCC induction and some of the pharmacotherapies imp…
SERPIN mediates transcriptional control over pro-tumorigenic pathways including a phosphatidyl inositol 1,3 kinase delta mediated mechanism.
Dr. Guerra focuses on emerging signaling and immunoepigenetic variations around the theme of protease inhibitor mediation of various stages and forms of solid organ and metastatic tumorigenesis in …
Dr Guerra admits Serpin mediated cancer ablation is multivalent and pharmaceutically treacherous
Dr Dan Guerra reveals that serine protease inhibitors (Serpins) are endogenous proteins that block protease-mediated metastasis and cancer associated fibroblast activation in some tumor microenvironm…
Introduction to Proteases and Protease Inhibitors as Prolegomena to Specific HCC pathophysiology
Dr.Guerra of Authentic Biochemistry provides a primer on polypeptide proteases and their mode of action as well as their control via processing and inhibition in clinical medicine
HCC Episode VII. Dr Guerra tackles the pathogenecity of the serine proteinase inhibitor paradigm . 08 JUne 2019
Serine proteinases and their peptide inhibitors, the SERPINS, have a role to play in liver pathology and disease potentiation leading to subcellular protein aggregation, enhanced inflammation and u…
Hepatocellular Carcinoma Pathobiochemistry Chapter/Lecture V from Dr. Daniel J. Guerra. Authentic Biochemistry.28 May 2019.
In this segment I provide more discussion of the published evidence linking glycolytic pathway enzymes to HCC progression. The expression of certain interfering RNA's that differentially regulate gen…
Dr Guerra Characterizes How Glycolytic Enzymes Proxy Oncogenically in Prodromal Hepatocellular Carcinoma. 26 May 2019
Dr. Guerra of Authentic Biochemistry continues with the 4th in a series of HCC lectures from the primary research literature by explaining the interacting roles of pyruvate kinase M2 and phosphofruct…
Dr Guerra introduces the pseudo-paradoxical irony of Pyruvate kinase M2 expression toward the biochemical Aetiology of HCC
Authentic Biochemistry's host, Dr Dan Guerra, continues his in depth cellular and molecular discussion of hepatocellular carcinoma (HCC) by introducing the non-universal yet a priori role for the gl…
Authentic Biochemistry Podcast. Dr. Dan Guerra presents Heptaocellular Carcinoma Part II: Metabolic and Signal Transduction Cascades
Dr Guerra takes a deeper dive into the hormonal and subcellular dysfunctional arrays linking obesity to Non-alcoholic Steatohepatitis (NASH) and Hepatocellular Carcinoma
Dr Guerra Starts his podcast lecture sequence on Obesity and Hepatocellular Carcinoma. Series session#1
This is Part One of what will be a 3-5 part sequence of podcast lectures giving Authentic Biochemical discussion concerning the links between obesity , sedentary lifestyle, alcohol consumption and i…
HDAC 4 is a positive player in ALS muscle since it is not a functional histone deacetylase: The complexity of motor neuron disease reveals not-so-subtle differences in protein function
Because HDAC4 closely resembles the structural component of the superfamily of histone deacetylases, in might be assumed it functions to catalyze the removal of LYS bound acetate. But since HDAC4 do…
Dr Guerra continues : Glutamate induced ferroptosis involves lipid peroxidation and ceramide production leading to an inflammatory response in neurodegeneration
Dr Daniel Guerra or VerEvMed and AB podcast provides the second part of his discussion concerning excitotoxic glutamate inducing aSMASE mediated neurodegeneration involving iron and the depletion of …
Dr Daniel Guerra introduces a novel PCD pathway- ferroptosis- that is linked to excitotoxicity and lipid peroxidation leading to neurodegeneration. Part I
This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research (JLR 2018 .59:312pp.) and develops s…
Authentic Biochemistry #3. Dr Guerra verifies the evidence to a future biochemical prolegomena for Alzhiemer's Disease
In this podcast, Dr Daniel Guerra of Authentic Biochemistry and VerEvMed endeavours to examine the bioenergetic and pro-inflammatory prodromal patho-biochemistry of age-onset Alzheimer's Disease us…
The Diaeventontology of Biological Systems
Dr. Daniel J. Guerra introduces his paradigmatic shift for understanding biochemical phenomena as prolegomena to understanding Alzheimer's Disease.
Introduction to Authentic Biochemistry Podcast
Dr Daniel Guerra of Authentic Biochemistry in his initial podcast introducing the show and starting off with initial content on current Alzheimer's Disease research