A podcast for physicians about evidence based medicine in rheumatology. Each week we'll critique and apply a paper in the medical literature.
Exciting episode this week! This is the FIRST of a new podcast series entitled Rheum4Debate, an Oxford style debate show for the field of rheumatology. We are planning to release one episode a mont…
This week a nice case control study out of Mayo challenged my own bias against MTX in GCA. This prompted a deep dive into the literature, including 3 RCTs and meta analysis. At the end of the day, …
The FDA recently approved romosozumab for high risk post menopausal osteoporosis, but gave it a black box warning for cardiovascular disease. This week I'll cover the data that led to it's approval …
This week I pair the recently published TRACE-RA trial assessing the efficacy of atorvastatin in primary prevention of cardiovascular disease. It offered a great opportunity to also go after the rece…
This week I discuss the phase 2 trial on baricitinib in SLE. Though it's early times (and the total flop of rituxan in ME/CFS recently can attest to this), this was a large phase 2 and I'm hopeful i…
#RheumJC week! I hope you all tuned into the online journal club #RheumJC, but if you did not I put up a podcast about the paper we discussed. Yet another epidemiological misadventure into unmeasure…
In this week's episode I depart briefly from discussing papers in the rheumatology literature to dive headfirst into the recent controversy over eggs and cardiovascular disease. Our patients eat eggs…
This week I'll tackle an interesting topic in giant cell vasculitis - the utility of FDG PET. This was a good paper but one that I used to discuss important concepts, including negative predictive va…
Finally addressing this ultrasound business. I decided to cover two somewhat similar trials, which seem to come to the same conclusions regarding U/S and treat to target strategies. However, the qu…
This week we tackle two RCTs and try to figure out what to do with etanercept, methotrexate, and placebo (or the lack thereof). Good opportunity for jumping into more PsA trials in the near future -…
We're back! This week I discuss work I did for the rheumatology winter clinical symposium on the quality of RCTs in the rheumatologic literature. Be sure to follow the twitter handle for a descript…
Double episode this week and then I'll be taking the holidays off. I decided to combine two trials of immunotherapy for secondary prevention of cardiovascular disease, the CANTOS trial (canakinumab …
Interesting trial this week pitting an elaborate nurse led group against suboptimal usual care. Suboptimal usual care lost pretty badly, but what to make of this? And does it support the rheumatolo…
Great article that (kind of) proves something a lot of us already believed; non-opioids management of chronic pain is preferable to opioid management. Lots of caveats, there, as this was a pragmatic…
Every 25 episodes I'd like to step back and touch base about where the podcast is headed. Thanks to everyone who has been listening! Apologies for nothing exciting or useful this week.
Interesting trial this week evaluating a fixed schedule of rituximab vs. a tailored approach to therapy. See you all at ACR this week!
Solid RCT this week that may rock your faith in all those pesky knee injections! Worth a listen before you do another. Find the original article here as usual.
Great article this week on stress related disorders and their relationship with subsequent autoimmune disease. One of my favorite recent papers from my least favorite way to do a study! Remember, al…
Quick episode today on a small prospective trial on ustekinumab for giant cell arteritis. Papers can all be found here!
This weeks episode discusses the utility of the ACE level in sarcoidosis. Lots of LRs, sensitivty, and specificities today!