The Evidence Based Rheumatology Podcast
A podcast for physicians about evidence based medicine in rheumatology. Each week we'll critique and apply a paper in the medical literature.
- Update frequency
- every 13 days
- Average duration
- 15 minutes
- Episodes
- 102
- Years Active
- 2018 - 2025
E126: Risk Signals, JAKs, and SELECTIVE-ity
Covering an interesting but ultimately disappointing post hoc study of multiple upadacitinib trials in RA. Initially some hope for clarity in the "Do JAKs cause all the badness?" questions, but ultim…
E125: Adrenal Insufficiency after Stopping Prednisone
Interesting read this week - I cover a nifty little paper that presented data about adrenal insufficiency after stopping prednisolone, published in JAMA Open in March 2025.
Open Access Journal He…
e124: MTX vs Pred for Pulmonary Sarcoidosis: PREDMETH Study
Interesting NEJM trial this week comparing methotrexate to prednisone for pulmonary sarcoidosis.
Paper available here: https://www.nejm.org/doi/full/10.1056/NEJMoa2501443
E123: Upadacitinib for Giant Cell Arteritis: SELECT-GCA
Podcast this week about the recently published SELECT-GCA study, which evaluated the use of the janus kinase inhibitor upadacitinib (Rinvoq) for patients with new and relapsing GCA. Successful trial …
E122: Guidelines for Maybe Diagnosing HLH
This week I cover another of my newsletters, though I mostly use it as a skeleton to riff on a common (and challenging) issue for rheumatology consultants; diagnosing HLH. Check out the guidelines th…
E121: Obinutuzumab in SLE-LN
Another day, another b cell podcast. Seems to be all the rage! This week I discuss the recently published NEJM trial of the anti CD20 agent obinutuzumab in lupus nephritis. Worth a read and listen, p…
E120: Real Life Use of PEXIVAS-Low
What do you do when observational data and RCTs conflict? This week I'm covering the "real world PEXIVAS" study that was done by the French Vasculitis Study Group. Great read, interesting issues, hav…
E119: Teclistamab for Rheumatology Writ Large
One of my rare case-report podcasts, a topic that I typically avoid. The craze about CAR-T has also made me a little crazy, though, so I wanted to share what I think may be the ultimate destination f…
E118: The emerging risk of overdiagnosis in RA and PMR
Podcast this week about overdiagnosis! Currently one of my favorite topics and something that I think will be an emerging issue in our field. We recently published a Viewpoint in Lancet Rheumatology …
E117: Inebilizumab for IgG4-RD (MITIGATE)
New RCT in a new disease with a new drug! But is it as shiny as one would hope? Interesting discussion today about what a trial means, how it will affect practice, and how we could do better as a fie…
E116: A New Paradigm for PMR
Reading one of my recent newsletters this week, this one about PMR tapers. Be sure to subscribe at ebrheum.com if you want access to the visuals and upcoming editions!
E115: Benralizumab for EGPA - the MANDARA Study
Quick rundown of an important rheumatology RCT this week, discussing the IL-5 inhibitor benralizumab for the treatment of relapsing/refractory EGPA.
MANDARA Study: https://www.nejm.org/doi/full/10…
E114: Target Trials and STAR-RA with Rishi Desai
Important methodology podcast this week, covering a lot of ground with expert epidemiologist Rishi Desai. Really enjoyed our conversation and glad to be publishing today!
**House Keeping Note: we ac…
E113: CAR-T is Coming to Rheumatology
Exciting podcast this week about the upcoming / impending use of CAR-T in rheumatology. Highly recommend rheumatologists learn about this now; it's going to be a big thing for many years to come. In …
E112: Gabapentin is Trash
This week's podcast will be a quick read of one of my newsletters. The title basically speaks for itself! Find the newsletter and my other work at ebrheum.com
E111: PEXIVAS Subsets with Mike Walsh & Mats Junek
At ACR23 I had a twitter-disagreement about steroid tapers from PEXIVAS with Mike Walsh, the lead author on the PEXIVAS trial. He kindly agreed to join me for a moderated discussion. Loved hearing hi…
E110: Rheum4Debate - Screening for RA-ILD with Joshua Solomon and Scott Matson
Rheum4Debate is back!
In this episode I moderated a debate between two pulmonologists about RA-ILD. As a reminder, Rheum4Debate is an Oxford-style debate show, where two debators disagree over a moti…
E109: Abatacept for Pre-RA - the ARIAA Study
Nice study this week on an important topic. Can we prevent the development of rheumatoid arthritis by initiating DMARDs during a preclinical phase? Lots to discuss: what does it mean to be "pre-clini…
E108: Myositis Guidelines for Cancer Screening w/Alexander Oldroyd
Informative podcast this week with Dr. Alexander Oldroyd, the first author of the recently published "International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening." The ar…
E107: Fragility of SLE Randomized Controlled Trials
Quick methodology episode this week discussing the concept of "fragility" in randomized controlled trials of lupus. Really enjoyed discussing this paper and was grateful to have been a part of it. Ge…