Authentic Biochemistry
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
- Update frequency
- every day
- Average duration
- 37 minutes
- Episodes
- 998
- Years Active
- 2019 - 2025
Cytoepigenetics IX. c-MYC controls transcription of two dehydrogenases that alter the ratio of 2-HG/alphaKG thus controling epigenetic signatures on DNA and RNA in a cancer mouse model.DJGPhD.11May22
References
Dr Guerra's Lecture notes
Cell Chem Biol. 2020 May 21; 27(5): 538–550.e7
Circulation. 2020 Dec 15;142(24):2356-2370
CytoEpigenetics VIII. The epigenetic processors, TET and BRD4, mediate control over fatty acid oxidation, pyruvate metabolism, the electron tranport chain and OXPHOS. DJGPhD.8May22. Authentic Biochem
References
Dr Guerra's notes
Circulation. 2020 Dec 15;142(24):2356-2370
Cancer Science June 2014. 105(9)
Cytoepigenetics VIIB. Warburg glycolysis explained from an epigenetic perspective plus some details of DNA methylation/demethylation. DJGPhD. Authentic Biochemistry Podcast 06May2022
References
Dr. Guerra's notes
Cancer Res. 2011 May 1; 71(9): 3400–3409
Front. Neurosci., 17 May 2017
Cytoepigenetics VIIa. Micro RNA control over the electron transport chain and oxidative phosphorylation via binding to nuclear and mitochondrial transcripts. DJGPhD03.may 2022. Authentic Biochemistry
References
Dr Guerra's pathbiochemistry lecture notes
Cancer Res. 2011 May 1; 71(9): 3400–3409
CytoEpigenetics V!. The 'magmatic' alteration of nuclear and mitochondrial gene expression via microRNA processing and translocalization is under bioenergetic control. DJGPhD. 2 May 2022.
References
Radiol Oncol. 2021 Dec; 55(4): 379–392
Cytoepigenetics V. Small interfering and micro RNA mediate mitochondrial and nuclear transcripts thus rendering cell fate, bioenergetics, and immunogenicity. DJGPhD.29.4.22. Authentic Biochemsitry
References
Guerra lecture notes/ideas
Genes (Basel). 2014 Dec; 5(4): 865–886.
Molecular Therapy—Nucleic Acids (2015) 4, e252
Int. J. Mol. Sci. 2016, 17(5), 719
Cytoepigenetics IV. Using Raman and IR spectroscopy to analyze the physical chemistry of pyrimidine nucleotide methylation. Dr. Daniel J. Guerra. 26.4.22. Authentic Biochemistry Podcast Productions
References
J of Computational Chemistry 2011 Volume32, Issue10: Pages 2077-2083
Cytoepigenetics IIIB. The Geometrical constraints decribed by the valence shell electron pair repulsion in biochemical reactivity. DJGPhD.25.4.22
Dr Guerra organic chemistry notes and concepts
Cytoepigenetics IIIA. Dissection of the PPAR-gamma epigenetic retailoring. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 25.4.2022
Review mini lecture
Cytoepigenetics II. The First Principle of Biochemical Epigenetics and the dialectic of methylated promoter region PPAR-gamma and peroxisomal mitigation between rodent and human. DJGPhD.24.4.22
References
Dr Guerra's ideas and concepts
Cells. 2021 Jun; 10(6): 1355.
Cells. 2019 Mar; 8(3): 227.
CytoEpigenetics I. Introduction. Dr. Daniel J. Guerra . 22.4.22. Authentic Biochemistry Podcast Productions
References
Introductory remarks from Guerra's research
Trends in Cell Biology, 2017-06-01, Volume 27, Issue 6, Pages 453-463.
Authentic Biochemistry is moving to a remote geographical region but will do so seamlessly and with full dedication. Please SUBSCRIBE and take notice of the discussion I have recorded here. DJGPhD
Dr Guerra takes this episode to redouble the committment of Authentic Biochemistry to providea detailed analysis and synthesis of current biomedical research science based on peer-reviewed published …
Diabetes XXXVI. Coda. Final lecture in diabetic dyslipidaemia.
References
Dr. Guerra lipid lectures
Journal of Diabetes Research, 2016, Article ID 2372741, 12 pages
Lipids in Health and Disease 2013.12(1):98
Cell Reports 2022. 38, 110566
Diabetes XXXV. Rodent model adipose mitochondrial respiratory contribution to obesity control involves a selenium protein and UCP1 sulfenylation. Dr Daniel J. Guerra. Authentic Biochemistry.18.4.22
References
Dr. Guerra Lipid and Intermediary Metabolism lectures
Cell Reports 2022. 38, 110566
PNAS July 24, 2017 | 114 (32) 8649-8654
Diabetes XXXIV. White vs brown adipocytes and the role of transcription factors and metabolic enzyme expression to mediate bioenergetics vs.lipogenesis in store depot fat.DJGPhD.17.4.22. Authentic B.
References
Dr. Guerra's lipid lecture archives
PNAS July 24, 2017 | 114 (32) 8649-8654
Int J Mol Sci. 2019 Oct; 20(19): 4924
Diabetes XXXIII. Synthesis of lecture arc Part 2. Dr Daniel J. Guerra. Authentic Biochemistry Podcast Studios. 16.4.22
References
Dr. Guerra's notes
Diabetes XXXII. Fatty acid oxygenation and use of eicosanoid molecular species to regulate T2D-linked inflammation via the agonization of the nuclear receptor transcription factor PPAR.DJGPhD 15.4.22
References
Dr Guerra lipid lecture notes
Biophysical J. Volume 110, Issue 11, 7 June 2016, Pages 2397-2406
Am J Pathol. 2020 Sep; 190(9): 1782–1788
Diabetes XXXI. REDOX biochemistry mini-review and the roles of essential fatty acid elongation/desaturation metabolism and COX/LOX oxygenation as ligands for PPAR isoforms in T2D pharmacotherapy.
References
Dr. Guerra lecture material
Nutr J. 2014; 13: 17.
Diabetes XXX. The pleitropic roles of free fatty acids and PPAR's as mediating insulin sensitivity, intermediary metabolism and the inflammatory response in T2D.Dr Daniel J. Guerra 13.4.22. Authentic
References
Dr. Guerra lecture notes
Prog Neurobiol. 2018 Apr-May; 163-164: 27–58.
Arteriosclerosis, Thrombosis, and Vascular Biology. 2006;26:28–40
DiabetesXXIX. THe CNS axis of Obesity-linked T2D via alterations in PPAR transcription factor mediated expression of ameliorative hippocampal AMPAR and LTP neural transmission in Alzheimer's Discsease
References
Dr. Guerra's Lecture Notes
Journal of the American College of Nutrition. 2019. 38:8, 693-702.
Curr Diabetes Rev. 2020;16(8):797-806