This Week in Virology

Steve Goff returns to TWiV to discuss the work of his laboratory on how retroviral genomes are silenced in infected cells.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

At the University of Wisconsin-Madison, Vincent meets up with one of his virology heroes, Roland R. Rueckert, to talk about his research and his second career as a forest manager.

Host: Vincent Racan…

In the first episode for 2019, the TWiV team reviews the amazing virology stories of the past year.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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The TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice.

Hosts: Vin…

The TWiV hosts discuss the distribution of prions in the eyes of patients with sporadic Creutzfeldt-Jacob disease, and the origins and evolution of RNA viruses.

Hosts: Vincent Racaniello, Alan Dove, …

Vaccine scientist, pediatrician, and autism dad Peter Hotez talks about his new book, Vaccines Did Not Cause Rachel's Autism.

Host: Vincent Racaniello

Guest: Peter Hotez

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Michelle Flenniken joins TWiV to talk about honeybees and the work of her laboratory on honeybee viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

Guest:…

Raul Andino joins Vincent and Amy to talk about the finding that a cricket paralysis virus protein restricts RNA-based immunity in insects by regulating the activity and stability of the Argonaute pr…

At the University of Zürich, Vincent speaks with virologists Cornel Fraefel, Urs Greber, and Silke Stertz about their careers and their work on AAV2, adenovirus entry, and influenza virus.

Hosts: Vin…

The TWiVsters review isolation of a naturally occurring DNA virus from fruit flies, and the cell-type specific function of a small transmembrane protein encoded in an open reading frame upstream of t…

Team TWiV cover the discovery of another giant virus from 30,000 year old Siberian permafrost, and how viral aggregation accelerates the production of new infectious viruses and increases fitness, de…

The TWiVidae review universal influenza vaccines that are in clinical trials, and discovery of an atypical parvovirus that causes chronic kidney disease in middle aged, immunocompromised laboratory m…

The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer's Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.

Ho…

Vincent travels to Penn State College of Medicine in Hershey, PA to speak with Nick and Leslie about their careers and their work on human cytomegalovirus and retroviruses.

Host: Vincent Racaniello

G…

Brianne and Vincent tackle two studies that utilize infectious viruses to examine zoonotic potential of Bombali virus, a new ebolavirus from an insectivorous species in Sierra Leone, and a human mump…

Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex.

Hosts: Vincent Ra…

The TWiV team notes the passing of Tom Steitz, an outbreak of acute flaccid myelitis in the US, a continuing Ebola virus outbreak in DRC, respiratory vaccinia due to inhalation of ground up rabbit sk…

The TWiVumvirate reviews this years crop of Nobel Prizes, and how cells prevent leakage of mitochondrial double-stranded RNA into the cytoplasm, which would otherwise lead to the production of interf…

From the 13th International Symposium on dsRNA viruses in Belgium, Vincent speaks with Harry Greenberg about his career and his work on rotaviruses, noroviruses, hepatitis B virus, and influenza viru…

Anne Simon joins the TWiV team to talk about plant viruses, including plum pox virus that devastates nut and stone fruit trees, and a geminivirus protein that regulates viral DNA synthesis.

Hosts: Vi…