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The Chain: Protein Engineering Podcast - Podcast

The Chain: Protein Engineering Podcast

The Chain explores the lives, careers, research, and discoveries of protein engineers and scientists, the impact their work is having on the field, and where the industry is headed. Tune in to stay up-to-date on the newest advancements and to hear the stories that are impacting the world of biologics.

Life Sciences Science
Update frequency
every 20 days
Average duration
29 minutes
Episodes
80
Years Active
2019 - 2025
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Episode: 77 - Derek Lowe on AI and the US Biotech Ecosystem

Episode: 77 - Derek Lowe on AI and the US Biotech Ecosystem

September 16, 2025 | With the rise of AI and automation, what is the core human skill in drug discovery that is and will be valuable in the future? Derek Lowe, director of Chemical Biology Therapeuti…

00:42:25  |   Tue 16 Sep 2025
Alexey Lugovskoy Shares Decades of Experience in Starting Out and Founding Companies

Alexey Lugovskoy Shares Decades of Experience in Starting Out and Founding Companies

August 12, 2025 | Diagonal Therapeutics founder and CEO Alexey Lugovskoy discusses the key lessons learned over his illustrious career, starting from his childhood in the Soviet Union to founding his…

00:47:23  |   Tue 12 Aug 2025
Episode: 75 - Are Licensing Fees Required or Gatekeeping?

Episode: 75 - Are Licensing Fees Required or Gatekeeping?

July 15, 2025 | Are licensing fees required or gatekeeping? In this episode of The Chain, host Nimish Gera, vice president of Biologics at Mythic Therapeutics, and Ian Wilkinson, CEO of Gamma Protein…

00:32:30  |   Tue 29 Jul 2025
Episode: 74 - Keith Flaherty, President-Elect of AACR, on Public and Private Collabs, AI Optimism, and More

Episode: 74 - Keith Flaherty, President-Elect of AACR, on Public and Private Collabs, AI Optimism, and More

June 10, 2025 | In this bonus episode of The Chain, Daniel Chen, MD, PhD, founder and CEO of Synthetic Design Lab, returns for the Science Commune segment and speaks with Keith Flaherty, MD, FAACR, p…

00:47:23  |   Wed 11 Jun 2025
Episode: 73 - PANEL DISCUSSION: Near-Term Challenges for AI/ML in Biotherapeutic R&D

Episode: 73 - PANEL DISCUSSION: Near-Term Challenges for AI/ML in Biotherapeutic R&D

June 10, 2025 | This episode of The Chain features a panel discussion from May’s PEGS Boston. Moderated by Peter Tessier, Albert M. Mattocks professor of Pharmaceutical Sciences and Chemical Engineer…

01:01:21  |   Tue 10 Jun 2025
Episode: 72 - Pamela Barney on HR Lessons to Meet the Needs of Biotech

Episode: 72 - Pamela Barney on HR Lessons to Meet the Needs of Biotech

In this episode of The Chain, host Tariq Ghayur, PhD, Tariq Ghayur Consulting, LLC, talks with Pamela Barney, former associate director of HR, AbbVie, about her career within biotech/pharma organizat…

00:35:23  |   Tue 13 May 2025
PEGS Young Scientist Keynote Jessica Stark on the Role of Glycans in Cancer Research

PEGS Young Scientist Keynote Jessica Stark on the Role of Glycans in Cancer Research

In this episode of The Chain, host Brandon DeKosky, associate professor, speaks with MIT colleague Jessica Stark, Underwood-Prescott career development professor, about glycans and why they are impor…

00:28:38  |   Tue 15 Apr 2025
Episode: 70 -  Views on Machine Learning and AI in the Antibody and Protein Engineering Space

Episode: 70 - Views on Machine Learning and AI in the Antibody and Protein Engineering Space

March 11, 2025 | In this episode of The Chain, host Andrew Buchanan, principal scientist at AstraZeneca, and Andreas Plückthun, professor and head of biochemistry at the University of Zurich, discuss…

00:49:36  |   Wed 12 Mar 2025
Episode: 69 - Conversation with Sir Greg Winter on the 50th Anniversary of the Milstein and Köhler Paper

Episode: 69 - Conversation with Sir Greg Winter on the 50th Anniversary of the Milstein and Köhler Paper

February 21, 2025 | This episode marks the 50th anniversary of one of the most influential papers in biomedical science—the 1975 Milstein and Köhler paper on hybridoma technology, which paved the way…

00:50:36  |   Fri 21 Feb 2025
Episode: 68 - Changing the Game of Protein-Protein Interactions With Randolph Lopez

Episode: 68 - Changing the Game of Protein-Protein Interactions With Randolph Lopez

In this episode of The Chain, host Andrew Bradbury, CSO of Specifica, an IQVIA business, speaks with Randolph Lopez, CTO and co-founder of A-Alpha Bio, about how A-Alpha Bio is changing the game of p…

00:46:00  |   Tue 10 Dec 2024
Episode: 67 - Anthony Tolcher Discusses Oncology, Dual-Payload Technology, and the ADC Field

Episode: 67 - Anthony Tolcher Discusses Oncology, Dual-Payload Technology, and the ADC Field

November 12, 2024 | In this episode of The Chain, host Rakesh Dixit, PhD, DABT, president and founder of Bionavigen Oncology and Regio Biosciences, speaks with Anthony Tolcher, M.D., FRCPC, cofounder…

00:42:34  |   Tue 12 Nov 2024
Episode: 66 - John Lambert on Antibody Drug Conjugates Then, Now, & Beyond

Episode: 66 - John Lambert on Antibody Drug Conjugates Then, Now, & Beyond

October 15, 2024 | In this month’s episode of The Chain, host Rakesh Dixit, PhD, DABT, president and founder of Bionavigen Oncology and Regio Biosciences, and John Lambert, PhD, consultant, about ant…

00:39:43  |   Wed 16 Oct 2024
Episode 65- Tariq Ghayur on the Renaissance of Bispecifics and ADCs, AI, and More

Episode 65- Tariq Ghayur on the Renaissance of Bispecifics and ADCs, AI, and More

September 10, 2024 | In this episode of The Chain, host Nimish Gera speaks with Tariq Ghayur, of Tariq Ghayur Consulting, LLC and Entrepreneur in Residence, FairJourney Biologics (and a fellow host o…

00:31:55  |   Tue 10 Sep 2024
Episode: 64 - Peyton Greenside on AI’s Role in Antibody Engineering, Optimization, and More

Episode: 64 - Peyton Greenside on AI’s Role in Antibody Engineering, Optimization, and More

In this episode of The Chain, host Nimish Gera, Ph.D., vice president of biologics at Mythic Therapeutics, speaks with Peyton Greenside, CSO and co-founder of BigHat Biosciences, about the role of AI…

00:32:31  |   Tue 13 Aug 2024
Episode: 63 - Discussing Protein Signaling and Structural Biology With Andrew Kruse

Episode: 63 - Discussing Protein Signaling and Structural Biology With Andrew Kruse

In this episode of The Chain, host Brandon DeKosky, associate professor at MIT, speaks with Andrew Kruse, PhD, professor of biological chemistry and molecular pharmacology at Harvard University, abou…

00:38:18  |   Tue 16 Jul 2024
Episode: 62 - AI/ML in Antibody Discovery and Engineering: Reality, Hope, Future, and Hype

Episode: 62 - AI/ML in Antibody Discovery and Engineering: Reality, Hope, Future, and Hype

his special episode of The Chain features a panel of industry experts who discussed AI and ML in antibody discovery and engineering at this year’s PEGS Boston event. Peter Tessier, professor at the U…

01:03:57  |   Tue 11 Jun 2024
Episode: 61 -  Tomoyuki Igawa Discusses Leadership and His Experiences in Discovery and Development

Episode: 61 - Tomoyuki Igawa Discusses Leadership and His Experiences in Discovery and Development

In this episode of The Chain, host Tariq Ghayur, PhD, consultant and entrepreneur in residence, FairJourney Biologics, speaks with Tomoyuki Igawa, PhD, chief executive officer, Chugai Pharmabody Rese…

00:55:04  |   Tue 14 May 2024
Episode: 60 - Lesley Millar-Nicholson on Technology Licensing, Navigating Patents, and Building Teams

Episode: 60 - Lesley Millar-Nicholson on Technology Licensing, Navigating Patents, and Building Teams

This month The Chain shares a recent episode of the Lab Rats to Unicorns podcast. Lab Rats to Unicorns, hosted by John Flavin, aims to demystify the process of creating a great company in the life sc…

00:48:14  |   Tue 09 Apr 2024
Episode: 59 - Gabriel Rocklin on Protein Biophysics and Protein Design

Episode: 59 - Gabriel Rocklin on Protein Biophysics and Protein Design

In this month’s episode of The Chain, host Ben Hackel, professor of Chemical Engineering & Materials Science at the University of Minnesota, speaks with Gabriel Rocklin, assistant professor of Pharma…

00:33:10  |   Tue 12 Mar 2024
Episode: 58 - Janine Schuurman Reflects on the Key Lessons and Accomplishments of Her 20-Year Career

Episode: 58 - Janine Schuurman Reflects on the Key Lessons and Accomplishments of Her 20-Year Career

How does one maintain innovation in the antibody industry? In this episode of The Chain, host Tariq Ghayur, PhD, consultant and entrepreneur in residence, FairJourney Biologics, talks with Janine Sch…

00:55:05  |   Tue 13 Feb 2024
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