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Smart Biotech Scientist | Master Bioprocess CMC Development, Biologics Manufacturing & Scale-up, Cell Culture Innovation - Podcast

Smart Biotech Scientist | Master Bioprocess CMC Development, Biologics Manufacturing & Scale-up, Cell Culture Innovation

The Go-to Podcast for Biotech Scientists Who Want to Master Biopharma CMC Development and Biomanufacturing.

**TOP 10 LIFE SCIENCES PODCAST**

Are you ready to simplify bioprocess development and scale with confidence to reduce time to market?

Are you feeling overwhelmed by the complexity and guesswork of biologics development and biomanufacturing?

Do you wish you had more time to enjoy the beauty of science, without worrying about failing your cell culture process development and commercialization?

There's a way to simplify and streamline so you can remove complexity, skip trials and errors, deliver your groundbreaking therapy to clinics and market without delay, and still enjoy every single step.

I'm David Brühlmann, a biotech entrepreneur and strategic advisor who partners with C-level biopharma leaders to tackle one of our industry's biggest challenges: reducing manufacturing costs to make lifesaving therapies accessible to more patients worldwide.

Through engaging conversations with industry pioneers and practical insights from the trenches, this podcast tackles the critical challenges in bioprocess CMC development and manufacturing of recombinant proteins and cell and gene therapy products. We cut through the complexity so you can:

  • Master bioprocess development with confidence and clarity


  • Excel at scale-up and manufacturing of biologics


  • Transform your innovative therapy and manufacturing technology into market-ready solutions faster


  • Optimize manufacturing costs without compromising quality


  • Make data-driven decisions that reduce the risk of failure


I can’t wait to help you do biotech the smart way.

Grab a cup of coffee and your favorite notebook and pen. Now is the time to take your bioprocessing game to the next level.

Ready to transform your biomanufacturing journey? Let's dive in!

Next Steps:

Book a free call to reduce biomanufacturing costs and make lifesaving therapies more accessible: https://bruehlmann-consulting.com/call


🧬 Ready to accelerate your IND timeline? Get the proven CMC Dashboard that's guided successful mAb programs from chaos to submission: https://stan.store/SmartBiotech/p/cmc-dashboard-for-biotech-founders

Accelerate biologics development with expert guidance: https://bruehlmann-consulting.com

Visit the Website: https://smartbiotechscientist.com

Email us: [email protected]

Science Innovation Development Technology Life Sciences
Update frequency
every 3 days
Average duration
19 minutes
Episodes
187
Years Active
2023 - 2025
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66: Freezing and Thawing Cells: the Science Behind Cryopreservation w/ Mark Davison - Part 2

66: Freezing and Thawing Cells: the Science Behind Cryopreservation w/ Mark Davison - Part 2

Get ready to dive into the fascinating world of cryopreservation!

In this episode, we welcome Mark Davison, an experienced entrepreneur and CEO of Grant Instruments, leaders in laboratory equipment, t…

00:16:08  |   Thu 27 Jun 2024
65: Freezing and Thawing Cells: the Science Behind Cryopreservation w/ Mark Davison - Part 1

65: Freezing and Thawing Cells: the Science Behind Cryopreservation w/ Mark Davison - Part 1

Picture a world where we can freeze cells and bring them back to life perfectly intact.

In this episode, we're joined by Mark Davison, a leading expert in cryopreservation and CEO of Grant Instruments…

00:24:15  |   Tue 25 Jun 2024
64: Why Sound Waves Are the Future of Gene Therapy Bioreactors w/ Gabriel Dumy - Part 2

64: Why Sound Waves Are the Future of Gene Therapy Bioreactors w/ Gabriel Dumy - Part 2

Could sound waves be the revolutionary key to gene therapy manufacturing? In this episode, Gabriel Dumy, CTO and Co-founder at Kolibri, reveals how acoustic waves are set to transform cell harvesting…

00:21:52  |   Thu 20 Jun 2024
63: Why Sound Waves Are the Future of Gene Therapy Bioreactors w/ Gabriel Dumy - Part 1

63: Why Sound Waves Are the Future of Gene Therapy Bioreactors w/ Gabriel Dumy - Part 1

Are sound waves the key to revolutionizing gene therapy? In this groundbreaking episode, we sit down with Gabriel Dumy, CTO and Co-founder at Kolibri, a company revolutionizing the way we grow and en…

00:25:27  |   Tue 18 Jun 2024
62: Magnetic Bead Technology: The New Era in Downstream Processing w/ Nils Brechmann - Part 2

62: Magnetic Bead Technology: The New Era in Downstream Processing w/ Nils Brechmann - Part 2

Dive into the future of bioprocessing with Nils Brechmann, Marketing Manager at MAGic BioProcessing and co-inventor of the process applications, as we explore how magnetic bead technology is transfor…

00:15:16  |   Thu 13 Jun 2024
61: Magnetic Bead Technology: The New Era in Downstream Processing w/ Nils Brechmann - Part 1

61: Magnetic Bead Technology: The New Era in Downstream Processing w/ Nils Brechmann - Part 1

Dive into the latest episode as we explore how magnetic bead technology is revolutionizing downstream processing, promising higher yields and greater purity.

Our guest, Nils Brechmann, Marketing Manag…

00:19:22  |   Tue 11 Jun 2024
60: Next-Generation Sequencing: Transforming Science and Medicine w/ Jonathon Hill - Part 2

60: Next-Generation Sequencing: Transforming Science and Medicine w/ Jonathon Hill - Part 2

Unlock the future of epigenetics and join us for an insightful conversation with Jonathon Hill as he delves into the groundbreaking world of next-generation sequencing (NGS) and its transformative im…

00:20:37  |   Thu 06 Jun 2024
59: Next-Generation Sequencing: Transforming Science and Medicine w/ Jonathon Hill - Part 1

59: Next-Generation Sequencing: Transforming Science and Medicine w/ Jonathon Hill - Part 1

Curious about the latest advancements in next-generation sequencing (NGS) and how they are revolutionizing science and medicine?

In this episode, we delve into the cutting-edge developments of NGS wit…

00:16:46  |   Tue 04 Jun 2024
58: Crafting a Solid CMC Strategy: Key Factors and Common Pitfalls w/ Matthias Müllner - Part 2

58: Crafting a Solid CMC Strategy: Key Factors and Common Pitfalls w/ Matthias Müllner - Part 2

Dive into the realm of biotech with our latest episode as we unravel the enigma of Quality by Design (QbD) with Matthias Müllner, CEO of & Co-Founder bespark*bio, a company empowering viral vector-ba…

00:19:08  |   Thu 30 May 2024
57: Crafting a Solid CMC Strategy: Key Factors and Common Pitfalls w/ Matthias Müllner - Part 1

57: Crafting a Solid CMC Strategy: Key Factors and Common Pitfalls w/ Matthias Müllner - Part 1

Join us for an insightful episode as we dive into the world of bioprocess CMC development strategies with Matthias Müllner, CEO of & Co-Founder bespark*bio, a company empowering viral vector-based me…

00:17:14  |   Tue 28 May 2024
56: Cultivated Meat: A Promising Future or an Inevitable Bubble? w/ Steven Lang - Part 2

56: Cultivated Meat: A Promising Future or an Inevitable Bubble? w/ Steven Lang - Part 2

Is cultivated meat the food of tomorrow or just a passing trend? In this episode, we dive deep with Steven Lang, an expert in the field of cultivated meat. Steven sheds light on the intricate process…

00:15:07  |   Thu 23 May 2024
55: Cultivated Meat: A Promising Future or an Inevitable Bubble? /w Steven Lang - Part 1

55: Cultivated Meat: A Promising Future or an Inevitable Bubble? /w Steven Lang - Part 1

How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process…

00:22:45  |   Tue 21 May 2024
54: Bionic Bioreactors: The Key to Stress-Free Cell Cultivation w/ Patrick Bongartz - Part 2

54: Bionic Bioreactors: The Key to Stress-Free Cell Cultivation w/ Patrick Bongartz - Part 2

How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process…

00:19:19  |   Thu 16 May 2024
53: Bionic Bioreactors: The Key to Stress-Free Cell Cultivation w/ Patrick Bongartz - Part 1

53: Bionic Bioreactors: The Key to Stress-Free Cell Cultivation w/ Patrick Bongartz - Part 1

How can you provide stress-free cultivation conditions to achieve higher cell concentrations and quality? In a nutshell, bionic bioreactors and thus change bubble-free gas exchange change the game.

Jo…

00:18:20  |   Tue 14 May 2024
52: Unraveling the Complexity of Commercializing Cell and Gene Therapies w/ Wajiha Ali - Part 2

52: Unraveling the Complexity of Commercializing Cell and Gene Therapies w/ Wajiha Ali - Part 2

Does the process of commercializing cell and gene therapies seem complex and unclear to you?

Dive deep into the groundbreaking world of cell and gene therapies with our guest, Wajiha Ali, a strategy e…

00:25:41  |   Thu 09 May 2024
51: Unraveling the Complexity of Commercializing Cell and Gene Therapies w/ Wajiha Ali - Part 1

51: Unraveling the Complexity of Commercializing Cell and Gene Therapies w/ Wajiha Ali - Part 1

Are you finding the path to commercializing cell and gene therapies complex and uncertain?

Join us as we explore this intricate landscape with our guest, Wajiha Ali. As a strategy expert who believes …

00:19:26  |   Tue 07 May 2024
50: Decode Bioprocess Success: The Art of Stakeholder Management - Part 2

50: Decode Bioprocess Success: The Art of Stakeholder Management - Part 2

In the second part of "Decode Bioprocess Success: The Art of Stakeholder Management," we delve deeper into the strategies for effective stakeholder management in bioprocess development.

Through a step…

00:11:08  |   Thu 02 May 2024
49: Decode Bioprocess Success: The Art of Stakeholder Management - Part 1

49: Decode Bioprocess Success: The Art of Stakeholder Management - Part 1

In this episode, we embark on a journey to uncover the essential strategies for navigating stakeholder relationships in bioprocess CMC development projects.

We delve into the critical role of stakehol…

00:17:10  |   Tue 30 Apr 2024
48: Mastering Process Economics: Driving Down Costs in Antibody Production w/ Brian Kelley - Part 2

48: Mastering Process Economics: Driving Down Costs in Antibody Production w/ Brian Kelley - Part 2

Unlock the secrets to cost-efficient antibody therapeutics with Brian Kelley, Senior Vice President of Process Development at VIR Biotechnology.

In this illuminating episode, industry expert Brian Kel…

00:18:54  |   Thu 25 Apr 2024
47: Mastering Process Economics: Driving Down Costs in Antibody Production w/ Brian Kelley - Part 1

47: Mastering Process Economics: Driving Down Costs in Antibody Production w/ Brian Kelley - Part 1

Join us in this enlightening episode as we explore process economics with industry expert Brian Kelley. He is the Senior Vice President of Process Development at VIR Biotechnology.

Unraveling the myst…

00:16:55  |   Tue 23 Apr 2024
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