MRC CTU Podcasts
The Trial Talk podcast explores how our work at the MRC Clinical Trials Unit at UCL is improving health in the UK and worldwide. In this series, we hear from world-leading experts about the studies we carry out. We delve into trials on cancer, infections
- Update frequency
- every 27 days
- Average duration
- 23 minutes
- Episodes
- 25
- Years Active
- 2017 - 2024
International Clinical Trials Methodology Conference 2024 roundup - early careers edition
At the start of October, lots of the Unit’s clinical trials methodology researchers travelled to Edinburgh, for the 7th International Clinical Trials Methodology Conference (ICTMC).
ICTMC is the lar…
00:25:09 |
Wed 30 Oct 2024
Lessons from UKCTOCS, a large-scale trial in ovarian cancer screening
UKCTOCS (UK Collaborative Trial of Ovarian Cancer Screening) is one of the largest screening trials in ovarian cancer. More than 200,000 women from England, Wales and Northern Ireland took part in it…
00:26:57 |
Mon 05 Feb 2024
Careers in TB trials with Andrew Nunn and Sarah Meredith
In the first episode of our new Trial Talk series, Hanif Esmail and Conor Tweed take over the microphones to interview Andrew Nunn and Sarah Meredith, who have both recently retired from the Unit, ha…
00:28:56 |
Fri 26 Jan 2024
World AIDS Day (part 2): Bringing hope through research to young people living with HIV
Every year on 1st December, we mark World AIDS Day to show solidarity in the fight against HIV and AIDS, and to remember those who have sadly lost their lives.
Since the start of the global AIDS e…
00:19:01 |
Fri 01 Dec 2023
World AIDS Day (part 1): Closing the gap between adults and children
Every year on 1st December, we mark World AIDS Day to show solidarity in the fight against HIV and AIDS, and to remember those who have sadly lost their lives.
Since the start of the global AIDS e…
00:24:04 |
Fri 01 Dec 2023
Octopus (part 4): Involvement of people affected by MS with Susan Scott
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platf…
00:20:02 |
Thu 09 Nov 2023
Octopus (part 3): The patients’ experience with Dawn Lyle and Matthew Justin
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platf…
00:24:04 |
Thu 02 Nov 2023
Octopus (part 2): Introducing the trial with Jeremy Chataway
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platf…
00:24:10 |
Thu 26 Oct 2023
Octopus (part 1): The MS landscape with Jeremy Chataway, Dawn Lyle and Matthew Justin
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC CTU at UCL. Thanks to its multi-arm multi-stage platform design, Octop…
00:17:20 |
Thu 19 Oct 2023
Optimising treatments with the new MAMS-ROCI design
Innovative platform designs present an opportunity to run faster and more efficient clinical trials.
Clinical trials methodology is a research area that looks at how to improve the design, conduct…
00:24:28 |
Thu 21 Sep 2023
STAMPEDE (part 3): Impact and legacy with Max Parmar & Nick James
STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treat…
00:23:23 |
Thu 24 Aug 2023
STAMPEDE (part 2): The role of the patient voice with David Matheson, Max Parmar & Nick James
STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treat…
00:18:00 |
Thu 17 Aug 2023
STAMPEDE (part 1): A new era for prostate cancer research with Max Parmar & Nick James
STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treat…
00:18:03 |
Thu 10 Aug 2023
The REFINE trial: How can we improve the way we give cancer immunotherapy?
Immunotherapy drugs fight cancer by helping the immune system recognise and attack cancer cells. These drugs have revolutionised cancer treatment over the last decade, improving survival for many peo…
00:16:57 |
Tue 18 Jul 2023
How can clinical trials make the most of healthcare systems data?
Running a clinical trial means collecting a lot of data from the trial participants. But some of this data might be collected and stored in healthcare systems, as well as in clinical trial case repor…
00:25:39 |
Mon 26 Jun 2023
Neonatal infections (part 2): How the NeoSep1 trial will help treat sick newborns
Neonatal sepsis is a life-threatening infection that affects up to 3 million babies per year globally.
In an effort to identify better treatments, the NeoSep1 clinical trial evaluates new antibioti…
00:21:13 |
Fri 09 Jun 2023
Neonatal infections (part 1): The NeoOBS study and the global challenge of neonatal sepsis
214,000 newborn babies die of sepsis caused by infections that are resistant to antibiotics every year. This is a major problem worldwide, but disproportionally affects low- and middle- income countr…
00:23:52 |
Mon 22 May 2023
The STREAM2 trial: How should we treat multi-drug resistant tuberculosis?
For World TB Day, this episode explores the global burden of tuberculosis (TB) and how growing antibiotic resistance can complicate treatment options. Andrew Nunn, a Professor of Epidemiology, discus…
00:19:59 |
Fri 24 Mar 2023
Ovarian cancer screening: The results of the UKCTOCS trial
Around 4000 women die of ovarian cancer in the UK each year. It is often diagnosed at an advanced stage, making treatment difficult. The UK Collaborative Trial of Ovarian Cancer Screening, known as t…
00:17:10 |
Thu 13 May 2021
Andrew Nunn talks medical statistics, TB, and Algerian nomads (Part 2)
Andrew Nunn joined the MRC’s Tuberculosis & Chest Diseases Unit as a statistician in 1966. During the next 20 years he was directly involved in the design, conduct and analysis of the programme of tr…
00:35:05 |
Mon 29 Oct 2018
Disclaimer: The podcast and artwork embedded on this page are the property of MRC Clinical Trials Unit at UCL. This content is not affiliated with or endorsed by eachpod.com.