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Mendelspod Podcast - Podcast

Mendelspod Podcast

The 21st is the Century of Biology. A radical advancement in the knowledge of basic biology and human disease is transforming our world. We interview the heroes beneath the headlines.

News Tech News Natural Sciences Science & Medicine
Update frequency
every 5 days
Average duration
27 minutes
Episodes
503
Years Active
2014 - 2025
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The Future of Diagnostics Reimbursement with Bruce Quinn

The Future of Diagnostics Reimbursement with Bruce Quinn

We toss the term "precision medicine" around with ease today, and yet payers continue to refuse to pay for diagnostic tests.
These are tests that might indicate which treatment will work for a specifi…
00:23:16  |   Thu 12 Nov 2015
Framingham for the Modern Era: Josie Briggs on the Precision Medicine Initiative

Framingham for the Modern Era: Josie Briggs on the Precision Medicine Initiative

Josie Briggs is Director of the National Center for Complementary and Integrative Health (NCCIH) at the NIH. She is also currently serving as interim director of the president’s new Precision Medici…
00:19:23  |   Wed 04 Nov 2015
Do Alternate Proposals to Regulate LDTs Stand a Chance?

Do Alternate Proposals to Regulate LDTs Stand a Chance?

As the FDA works away on final guidance for regulating LDTs, various professional groups unhappy with the course of the FDA have put together and hurried their own proposals up to Captiol Hill. The D…
00:24:05  |   Thu 29 Oct 2015
Does the Reproducibility Project in Cancer Biology Offer a Model for a New Kind of Science Auditing?

Does the Reproducibility Project in Cancer Biology Offer a Model for a New Kind of Science Auditing?

Here on the show, we’ve talked about the lack of reproducibility for much of biological research. We’ve bandied around various percentages--is it 50% or up to 90% that can't be replicated? And we’v…
00:23:47  |   Tue 27 Oct 2015
After CMS Announcement, Peter Maag and CareDx Fight for Life

After CMS Announcement, Peter Maag and CareDx Fight for Life

By listening to him, you wouldn’t know that Peter Maag, the CEO of CareDx, was fighting to keep his company from the brink. We booked Peter for the show after news came out that CMS was once again th…
00:19:20  |   Thu 22 Oct 2015
The Goal Is De Novo Assembly in the Clinic, Says Jim Lupski, Baylor

The Goal Is De Novo Assembly in the Clinic, Says Jim Lupski, Baylor

Today’s story is one of a personal quest, of groundbreaking science, and the creation of a new movement in human genomics.

Jim Lupski is a professor at Baylor College of Medicine where he’s on the fro…
00:23:01  |   Tue 20 Oct 2015
Cliff Reid Says New Supersequencer Leads the Pack for High Throughput Clinical Sequencing

Cliff Reid Says New Supersequencer Leads the Pack for High Throughput Clinical Sequencing

Cliff Reid, CEO of Complete Genomics, is back on the conference circuit, touting a new product. After years of building his company to do sequencing as a service, Cliff presented data at last week's…
00:28:37  |   Fri 16 Oct 2015
Defending the Value of Biotech Innovation in California: Sara Radcliffe, CLSA

Defending the Value of Biotech Innovation in California: Sara Radcliffe, CLSA

Earlier this year, the California Life Sciences Association (CLSA) launched, becoming the first statewide policy and advocacy group for biotech. The new nonprofit, a merger between BayBio and the Cal…
00:21:10  |   Fri 09 Oct 2015
Long Read Sequencing Dramatically Improves Blood Matching: Steven Marsh, Anthony Nolan Institute

Long Read Sequencing Dramatically Improves Blood Matching: Steven Marsh, Anthony Nolan Institute

One of the popular questions on the program this past year is how those doing sequencing decide between the quality of Pacific Bioscience's long reads and the cheaper short read technology, such as t…
00:23:30  |   Tue 06 Oct 2015
The World of DIY Genomics with K T Pickard

The World of DIY Genomics with K T Pickard

K Thomas Pickard is not at all into sports cars. So when he hit midlife crisis, it wasn’t a Porsche or a golf club membership that would reenergize his quiet moments. Nope. K T got his genome seq…
00:28:17  |   Thu 01 Oct 2015
Sequencing in Space: Chris Mason, Cornell

Sequencing in Space: Chris Mason, Cornell

The last time we talked with Chris Mason of Weill Cornell Medical College the Supreme Court had just decided the controversial Myriad gene patent case. How forever ago two years can seem. Since the…
00:30:01  |   Thu 24 Sep 2015
Is the Future of Biology a Return to Chemistry? Carolyn Bertozzi, Stanford

Is the Future of Biology a Return to Chemistry? Carolyn Bertozzi, Stanford

Classes for the school year begin this week at Stanford University. New to the faculty is Carolyn Bertozzi, an American chemist who made her name across the bay at Berkeley and was wooed to Stanfo…
00:26:19  |   Tue 22 Sep 2015
Going Beyond the $1,000 Genome with Mark Gerstein

Going Beyond the $1,000 Genome with Mark Gerstein

Though recent guests at Mendelspod say we're not quite to the $1,000 genome, we're close enough to use that benchmark in genomics discussions. But what are we getting for that almost $1,000?

Mark Ger…
00:28:56  |   Thu 17 Sep 2015
Creating the Foundation of Genomics: Marc Salit, NIST

Creating the Foundation of Genomics: Marc Salit, NIST

What is a human genome? Well it’s the three billion letters of our DNA. But how is it measured? How do we know when we have it accurately represented?

These are questions that will have to be answe…
00:30:18  |   Thu 10 Sep 2015
Still Unhappy with FDA’s Plan to Regulate LDTs, Professional Lab Groups Go Direct to the Senate

Still Unhappy with FDA’s Plan to Regulate LDTs, Professional Lab Groups Go Direct to the Senate

It's no secret that America's molecular testing laboratories by and large are worried that the FDA's plan to regulate laboratory developed tests, or LDTs, will severely harm patients. Now they have a…
00:24:20  |   Tue 08 Sep 2015
A Diagnostic Success Story with Alka Chaubey, Greenwood Genetic Center

A Diagnostic Success Story with Alka Chaubey, Greenwood Genetic Center

Diagnostics can be a tough business. The FDA is making a strong push to bring more oversight. Obtaining reimbursement can be outright Sisyphean. And clinicians are slow on the uptake. All of whic…
00:25:13  |   Thu 03 Sep 2015
With Two New Easy-to-Use Sequencing Instruments, Thermo Readies for Primetime in the Clinic

With Two New Easy-to-Use Sequencing Instruments, Thermo Readies for Primetime in the Clinic

The race to the $1,000 genome has been full of breathtaking advances, one after the other. But is next gen sequencing reaching maturity? Will there be that many more significant innovations?

This is …
00:21:11  |   Tue 01 Sep 2015
Here's Looking at Euclid

Here's Looking at Euclid

A slow week in life science left us scratching our heads about the purpose of some new studies.

The first, a major project to study the microbes in about 1,200 homes appeared under headlines such as t…
00:04:28  |   Fri 28 Aug 2015
Is This the Future of Clinical Trials for Cancer? Stanley Hamilton on the NCI’s New MATCH Trial

Is This the Future of Clinical Trials for Cancer? Stanley Hamilton on the NCI’s New MATCH Trial

It’s taken some time, but the NCI is finally sponsoring a big time clinical trial for cancer where the patients are organized by the genomic pathway that defines their cancer rather than the organ ty…
00:24:54  |   Thu 27 Aug 2015
Brian Kennedy and Aubrey de Grey on their Converging Approaches to Aging Research

Brian Kennedy and Aubrey de Grey on their Converging Approaches to Aging Research

Last week we attended the 2015 Rejuvenation Biotechnology Conference where we heard about the latest developments in aging research.

We were fortunate enough to sit down with two of the major figures …
00:21:10  |   Tue 25 Aug 2015
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