Manifold

In collaboration with her husband Malcolm Collins, Simone is an author (The Pragmatist's Guide to Life, Relationships, Sexuality, Governance, and Crafting Religion), education reform advocate (Collin…

Katherine Dee is a writer, journalist, and internet historian.

Steve and Katherine discuss:

0:00 Introduction

1:15 Katherine’s early life and background

21:52 Mass shootings, Manifestos, Nihilism, and In…

Marc Martinez is the director of Dream Big, a documentary about Gold's Gym and the golden age of bodybuilding in Venice and Santa Monica in the 1970s.

Steve and Marc discuss:

• (01:34) - Marc's backgroun…

Gilles Saint-Paul is Professeur à l'Ecole Normale Supérieure. He is a graduate of Ecole Polytechnique in Engineering and received his PhD from MIT in Economics. Gilles and Steve discuss the French el…

Steve discusses the competition between Microsoft and Google, the competition between the U.S. and China in STEM, China’s new IVF policy, and a Science Magazine survey on polygenic screening of embry…

Steve discusses Large Language Model AIs such as ChatGPT. 

0:00 How do LLMs work?

10:22 Impact of ChatGPT

15:21 AI landscape

24:13 Hallucination and Focus

33:09 Applications

39:29 Future Landscape

Reference…

Dominic Cummings is a major historical figure in UK politics. He helped save the Pound Sterling, led the Vote Leave campaign, Got Brexit Done, and guided the Tories to a landslide general election vi…

Sahil Lavingia founded Gumroad at the age of 19 and built it into a leading digital commerce platform. He is the author of The Minimalist Entrepreneur and an investor in early-stage startups.

Steve an…

Geoffrey Miller is an American evolutionary psychologist, author, and a professor of psychology at the University of New Mexico. He is known for his research on sexual selection in human evolution.

Fo…

Anna I. Krylov (Russian: Анна Игоревна Крылова) is a Professor of Chemistry at the University of Southern California (USC), working in the field of theoretical and computational quantum chemistry.

Kry…

Abdel Abdellaoui is Assistant Professor of Genetics in the Department of Psychiatry, Amsterdam UMC, University of Amsterdam.

Abdel Abdellaoui is a geneticist who has been involved in a wide range of s…

Richard Sander is Jesse Dukeminier Professor at UCLA Law School. AB Harvard, JD, PhD (Economics) Northwestern.

Sander has studied the structure and effects of law school admissions policies. He coined…

Peter Byrne is an investigative reporter and science writer based in Northern California. His popular biography, The Many Worlds of Hugh Everett III - Multiple Universes, Mutual Assured Destruction, …

Jeffrey D. Sachs is a world-renowned economics professor, bestselling author, innovative educator, and global leader in sustainable development. Professor Sachs serves as the Director of the Center f…

Rob Henderson grew up in foster homes in California, joined the Air Force at 17, attended Yale on the G.I. Bill, and is currently a Gates Fellow at Cambridge University (UK). He is an acute observer …

Professor Lyle Goldstein recently retired after 20 years of service on the faculty of the U.S. Naval War College (NWC). During his career at NWC, he founded the China Maritime Studies Institute (CMSI…

The guest for this episode is a recent graduate of Harvard College, now pursuing a STEM PhD at another elite university. We have withheld his identity so that he can speak candidly.

Steve and his gues…

Richard Lowery is a professor of finance at the McCombs School of Business at the University of Texas, Austin. In this conversation, he describes the ideological climate of his university and the con…

Tim Palmer is Royal Society Research Professor in Climate Physics, and a Senior Fellow at the Oxford Martin Institute.

He is interested in the predictability and dynamics of weather and climate, inclu…

Kishore Mahbubani is Distinguished Fellow at the Asia Research Institute, National University of Singapore. 

Kishore enjoyed two distinct careers: in diplomacy (1971 to 2004) and in academia (2004 to…