Beginner's Mind

How do you succeed in a business where being wrong is the norm?

Marc Penkala has lived both sides of the table: as an entrepreneur who built, sold, and failed with companies—and now as a venture capit…

Here’s the harsh truth: If your business model can’t survive a spreadsheet, it won’t survive the market.

Every year, ambitious founders pour months into product, pitch, and brand—yet the single bigges…

Why do Europe’s brightest founders still feel forced to leave for Silicon Valley—no matter how much money or talent we pour into the region?
 Every year, ambitious startups across Europe and CEE strug…

Still trying to optimize your health with guesswork and generic advice?
Most people settle for “one-size-fits-all” supplements and hope for the best-missing out on the breakthroughs that only real dat…

How do you lead at the cutting edge of health, data, and AI—while staying deeply human?

Angeli Möller has led global data science teams across pharma giants, co-founded one of Europe’s most ambitious …

Most founders add layers to gain control. Reed Hastings built an empire by removing them. 

This episode unpacks No Rules Rules—the leadership playbook behind Netflix’s rise from a DVD mail service to …

 Most cancer drugs fail. Not because the science is wrong—because we’re solving the wrong problems.

The cost? Over $2 billion per failure. And for the patient waiting on a miracle—there’s no second ch…

Europe has the science. The talent. The breakthroughs.

But when an idea feels too uncertain, our systems shut it down before it has a chance to breathe.

And with every safe bet… we quietly lose the nex…

What if the only way to save the planet... is to cool it?
Not figuratively—literally.
Because the heatwaves, floods, and fires you’ve seen so far? They’re just the beginning.

🌍 Emissions keep rising. …

What if your business ran like a well-designed machine—one that could evolve, self-correct, and outperform your competition over decades?

In this episode, I unpack Principles by Ray Dalio, the billion…

What does it take to turn extreme adversity into extraordinary leadership? Suzanne Heywood’s life reads like a novel—shipwrecked at seven, isolated at sea for a decade, forging her father’s signature…

ATMPs, gene therapies, and cancer breakthroughs are here—but outdated regulations, high costs, and logistical bottlenecks are blocking access. What needs to change for hospitals to deliver these cure…

In 2021, biotech IPOs were soaring. Valuations hit record highs. Investors were throwing money at anything that moved.

Then… the market crashed. Funding dried up. Growth stalled. Biotech founders and …

🚀 Most investors chase consensus. The best ones? They bet against it.

If everyone agrees on an investment, it’s probably not bold enough. That’s why the greatest venture capitalists don’t just follow …

What if your greatest asset in business was how you think under pressure?

In this episode, I dive into The Venture Mindset by Alex Dang and Ilya Strebulaev, unpacking seven transformative lessons draw…

What does it take to redefine venture capital while empowering founders to disrupt industries and drive meaningful change? Meet Dan Bowyer, a bold investor from Superseed VC reshaping the game with a…

What makes a year unforgettable? Is it the challenges conquered, the bold ideas pursued, or the connections that shaped us?

As 2024 comes to a close, this special episode celebrates the lessons, break…

Our global food systems are at a breaking point. Climate change, geopolitical tensions, and industrial farming are pushing us closer to food insecurity every day. Can we find a way to feed 10 billion…

What does it take to tackle the world's biggest challenge—climate change—while driving profit and innovation? Meet Doerte Hirschberg, a visionary investor reshaping industries with bold ideas and dat…

What if your greatest advantage in business was how you think about the future?

In this episode, I explore Richer, Wiser, Happier by William Green, unpacking seven actionable lessons inspired by legen…