AI + a16z
Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.
- Update frequency
- every 8 days
- Average duration
- 43 minutes
- Episodes
- 56
- Years Active
- 2024 - 2025
What DeepSeek Means for Cybersecurity
In this episode of AI + a16z, a trio of security experts join a16z partner Joel de la Garza to discuss the security implications of the DeepSeek reasoning model that made waves recently. It's three s…
Agents, Lawyers, and LLMs
In this episode of AI + a16z, Aatish Nayak, head of product at Harvey, sits down with a16z partner Kimberly Tan to share his experience building AI products for enterprises — including the legal prof…
Reasoning Models Are Remaking Professional Services
In this episode of AI + a16z, a16z partner Alex Immerman sits down with Hebbia founder and CEO George Sivulka to discuss the potential for reasoning models and AI agents to supercharge knowledge-work…
Data Management for Enterprise LLMs
In this episode of AI + a16z, Fivetran cofounder and CEO George Fraser and a16z partner Guido Appenzeller discuss how LLMs fit into the data management picture within large enterprises. In order to t…
From NLP to LLMs: The Quest for a Reliable Chatbot
In this episode of AI + a16z, a16z General Partner Martin Casado and Rasa cofounder and CEO Alan Nichol discuss the past, present, and future of AI agents and chatbots. Alan shares his history workin…
Best of the Year: Building AI Companies
A 2024 highlight reel, featuring founders sharing their insights, advice, and experiences building AI companies — from foundation-model labs to vertical applications. Topics include:
- Building AI tools…
Can AI Agents Finally Fix Customer Support?
In this episode of the AI + a16z podcast, Decagon cofounder/CEO Jesse Zhang and a16z partner Kimberly Tan discuss how LLMs are reshaping customer support, the strong market demand for AI agents, and …
REPLAY: Scoping the Enterprise LLM Market
This is a replay of our first episode from April 12, featuring Databricks VP of AI Naveen Rao and a16z partner Matt Bornstein discussing enterprise LLM adoption, hardware platforms, and what it means…
Building Developers Tools, From Docker to Diffusion Models
In this episode of AI + a16z, Replicate cofounder and CEO Ben Firshman, and a16z partner Matt Bornstein, discuss the art of building products and companies that appeal to software developers. Ben was…
The Best Way to Achieve AGI Is to Invent It
Longtime machine-learning researcher, and University of Washington Professor Emeritus, Pedro Domingos joins a16z General Partner Martin Casado to discuss the state of artificial intelligence, whether…
Neural Nets and Nobel Prizes: AI's 40-Year Journey from the Lab to Ubiquity
In this episode of AI + a16z, General Partner Anjney Midha shares his perspective on the recent collection of Nobel Prizes awarded to AI researchers in both Physics and Chemistry. He talks through ho…
How GPU Access Helps AI Startups Be Agile
In this episode of AI + a16z, General Partner Anjney Midha explains the forces that lead to GPU shortages and price spikes, and how the firm mitigates these concerns for portfolio companies by supply…
DisTrO and the Quest for Community-Trained AI Models
In this episode of AI + a16z, Bowen Peng and Jeffrey Quesnelle of Nous Research join a16z General Partner Anjney Midha to discuss their mission to keep open source AI research alive and activate the …
Balancing AI Expertise and Industry Acumen in Vertical Applications
In this episode of AI + a16z, Ambience cofounder and chief scientist Nikhil Buduma joins Derrick Harris to discuss the nuances of using AI models to build vertical applications (including in his spac…
AI, SQL, and the End of Big Data
In this episode of AI + a16z, a16z General Partner Jennifer Li joins MotherDuck Cofounder and CEO Jordan Tigani to discuss DuckDB's spiking popularity as the era of big data wanes, as well as the app…
The Researcher to Founder Journey, and the Power of Open Models
In this episode of the AI + a16z podcast, Black Forest Labs founders Robin Rombach, Andreas Blattmann, and Patrick Esser sit down with a16z general partner Anjney Midha to discuss their journey from …
Why Computer Science Subsumed Biotech
In this episode, a16z General Partner Vijay Pande walks us through the past two decades of applying software engineering to the life sciences — from the Folding@Home project that he launched, through…
Democratizing Generative AI Red Teams
In this episode of the AI + a16z podcast, a16z General Partner Anjney Midha speaks with PromptFoo founder and CEO Ian Webster about the importance of red-teaming for AI safety and security, and how b…
Augmenting Incident Response with LLMs
In this episode of the AI + a16z podcast, Command Zero cofounder and CTO Dean de Beer joins a16z's Joel de la Garza and Derrick Harris to discuss the benefits of training large language models on sec…
Scaling AI for the Coming Data Deluge
In this episode of the AI + a16z podcast, Anyscale cofounder and CEO Robert Nishihara joins a16z's Jennifer Li and Derrick Harris to discuss the challenges of training and running AI models at scale;…