a16z Podcast

with Atul Butte (@atulbutte), Daphne Koller (@daphnekoller), and Vijay Pande (@vijaypande)

Whether you’re an academic seeking to move out of research and into industry, or simply interested in workin…

with Ray Dalio (@raydalio), Alex Rampell (@arampell), and Sonal Chokshi (@smc90)

Can one really apply the lessons of history and of the past to the present and the future, as a way to get what they w…

Many of the healthcare headlines lately have been about consolidation in the industry: Walmart and Humana; Aetna and CVS; Amazon, JP Morgan, and Berkshire Hathaway. But what does it all mean for pati…

The creation of each new biotechnology enables a tool, a therapy, or a diagnostic: a molecule, a protein, an app, a platform. And the process underneath isn't just complex in the science and engineer…

Hypothesis, test, revise -- that's science. Engineering, however, doesn't quite go that way: You have parts you know and understand (like legos), and then you use those parts to design and build some…

with Lisa Hawke (@ldhawke) and Steven Sinofsky (@stevesi)

Given concern around data breaches, the EU Parliament finally passed GDPR (General Data Protection Regulation) after four years of preparatio…

with Nicole Forsgren (@nicolefv), Jez Humble (@jezhumble) and Sonal Chokshi (@smc90)

From the old claim that "IT doesn't matter" and question of whether tech truly drives organizational performance, …

Few operators become VCs, and even fewer go back to leading companies... so how does these perspectives change how one leads? Obviously, it's a lot easier to think of a solution than execute on one..…

Leadership is not just about management, but about passion, a bit of humor, and resilience. General partner Peter Levine and Dick Costolo (entrepreneur, former CEO of Twitter, and erstwhile comedian)…

Focusing only on the technical, "crunchy, wonky stuff" behind policies or products sometimes misses the humanity at the center of why we're doing the thing in the first place. Because systems -- whet…

with Kristen Fortney (@kpfortney), Jeff Kaditz (@jeffkaditz), David Sinclair (@davidasinclair), and Hanne Tidnam (@omnivorousread)

Even without a mythical fountain of youth, scientific advances have …

with Cristina Cordova (@cjc), Augusto Marietti (@sonicaghi), Laura Behrens Wu (@laurabehrenswu), and Sonal Chokshi (@smc90)

APIs (application programming interfaces), observe the guests in this episo…

What happens when monolithic architectures are broken down into containers and microservices (or when things are broken down into smaller units, not just in infrastructure but perhaps even in company…

When most people think of space, they think of outer space: Mars, billionaires with rockets, and the “final frontier”. But space innovation is actually playing out right now -- in an immediate and mo…

with Joel de la Garza, Stina Ehrensvärd, Niels Provos, and Martin Casado

Given the heated discussions around security and the c-word (“cyber”), it’s hard to figure out what the actual state of the in…

with Martin Casado (@martin_casado), Michel Feaster (@michelfeaster) and Sonal Chokshi (@smc90)

The purpose of category creation, argue the guests in this episode of the podcast, isn't just about mak…

with Adam Bry (@adampbry), Chris Dixon (@cdixon), and Hanne Tidnam (@omnivorousread)

Now that we've finally reached the age of the truly autonomous commercial small drone -- and in this case, a self-…

Once upon a time it was inconceivable that a company in Silicon Valley could make content that was any good; the running joke, shares Marc Andreessen, "was like, what are we gonna do -- we're gonna f…

Every large company -- especially ones that have been around for a long time -- goes through multiple cycles of change. But how do you know where to go next, and when, and how? The management literat…

As people begin to gain access to information that was previously left to only trained specialists, a new set of asset classes are being created -- and they are changing the way we think about everyt…