09: What the HEK is new in immunotherapy? (2024 recap)

To end off the year Grace and Gillian dive into some of the scientific findings and news they found most interesting in the immunotherapy field for 2024! We hope this gets you excited about the progress of immunotherapy and the many breakthroughs to come!

For more information on the immunotherapies discussed here check out the links below:

Lifileucel, the first FDA-approved TIL product: https://www.cancer.gov/news-events/cancer-currents-blog/2024/fda-amtagvi-til-therapy-melanoma

CAR T cell therapy for autoimmune disease: https://www.nejm.org/doi/full/10.1056/NEJMoa2308917 and https://www.science.org/content/article/breakthrough-cancer-immunotherapy-now-taking-aim-autoimmune-disease

7th approved CAR T cell product (AUCATZYL): https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-obecabtagene-autoleucel-adults-relapsed-or-refractory-b-cell-precursor-acute

First FDA-approved CAR T cell product for CLL: https://www.lls.org/news/fda-approves-first-car-t-cell-therapy-chronic-lymphocytic-leukemia#:~:text=Rye%20Brook%2C%20N.Y.%2C%20March%2019,not%20responded%20to%20previous%20treatments.

Breast cancer vaccine: https://ascopost.com/news/november-2024/breast-cancer-vaccine-could-be-preventive-well-tolerated-in-high-risk-patients/

FDA approval of first TCR therapy for synovial sarcoma (Afami-cel): https://www.cancer.gov/news-events/cancer-currents-blog/2024/fda-tecelra-synovial-sarcoma-mage-a4

Personalized engineered TCR TIL therapy phase II study: https://www.cancer.gov/news-events/press-releases/2024/personalized-immunotherapy-shrinks-solid-tumors

Long term checkpoint blockade therapy followup: https://news.weill.cornell.edu/news/2024/09/long-term-metastatic-melanoma-survival-dramatically-improves-on-immunotherapy

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Interested in learning more about immunotherapy? Check out our other episodes and give us a follow on instagram @wthisimmunotherapy and twitter @WTHisImmunoT! And check out our website ⁠wthisimmunotherapy.com⁠. Or feel free to reach out to us at ⁠[email protected]⁠ if you have any questions or any ideas for episodes!

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Creators & Producers: Gillian Savage, Grace Bernard, and Dr. Pauline Loos 

Podcast Logo is designed by Mia Portelance 

Music is by Lara Antebi (⁠https://laraantebi.bandcamp.com/⁠)