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Patrick Hsu on betting big: CRISPR, AI, and building science in the open

Author
Benchling
Published
Fri 01 Aug 2025
Episode Link
https://www.benchling.com/transcribed?wchannelid=4czj6egqey&wmediaid=uv7xpwqjeo

Patrick Hsu reflects on the early days of CRISPR, the power of mentorship, and how AI and open science will reshape the future of research.

(00:00) Introduction to Patrick Hsu

(01:06) Realizing how big CRISPR would become

(06:20) Why Feng Zhang's lab is so high-impact

(14:23) How to spot a breakthrough before it happens

(18:18) Where the U.S. can't compete with China — and where it can

(22:13) How will AI transform the industry — and what's still missing

(29:41) Why everyone wins with open science

(36:42) Building products that people actually want

(43:13) New funding models in science

(48:26) On starting college at 15 — and a lab at 22

(55:04) Lightning round

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