TWiV 336: Brought to you by the letters H, N, P, and Eye

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The TWiVsters explore mutations in the interferon pathway associated with severe influenza in a child, outbreaks of avian influenza in North American poultry farms, Ebolavirus infection of the eye weeks after recovery, and Ebolavirus stability on surfaces and fluids.

This episode is sponsored by @ASM Conferences and ASM Microbe

• Life threatening influenza and IRF7 deficiency (Science)


• Whole exome sequencing (Wikipedia)


• Herpes encephalitis in children with Trif deficiency (TWiV 175)


• Avian influenza in the US (USDA, ProMedMail, CDC)


• Ebola eye (NEJM, NYTimes)


• Viral persistence (Virology lectures, pdf)


• Uveitis (National Eye Institute)


• Image credit


• Stability of Ebolavirus on surfaces (EID)


• Ignorance with Stuart Firestein (TWiV Special)


• Letters read on TWiV

Timestamps by Jennifer. Thank you!

Alan - Winogradsky time-lapseRich - Missing link in evolution of complex cellsKathy - GrantomeDickson - National Geographic Landscape Photo of the DayVincent - PyMol and Chimera

Mauricio - Vax!