TWiV 1028: Asymptomatic SARS-CoV-2 infection and T cells

TWiV reviews approvals of the first gene therapy for severe hemophilia A in adults and a monoclonal antibody to prevent RSV respiratory disease in babies and toddlers, and a common allele of HLA that mediates asymptomatic SARS-CoV-2 infection through pre-existing T cell immunity due to previous exposure to common cold coronaviruses.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker

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• MicrobeTV Discord Server
• First gene therapy for hemophilia A approved (FDA)
• Luxurna, gene therapy for vision loss (FDA)
• Anti-RSV monoclonal antibody approved (FDA)
• Trial of single-dose Nirsevimab (NEJM)
• Letters read on TWiV 1028
• Timestamps by Jolene. Thanks!

Dickson – Phoenix hits 110 degrees for the 19th day in a row, setting national record Brianne – James Webb Telescope One Year Anniversary Photo Kathy – Drone awards photos Alan – WHO Film Festival winners Vincent – Thinking, Fast and Slow by Daniel Kahneman

David – The Mass Extinction Debates: A Science Communication Odyssey

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]