In this episode of The Spoon Podcast, Michael Wolf sits down with Mark Cuban for a wide-ranging conversation recorded live at the SKS 2025. Mark and Mike discuss the transformative power of AI, exploring why Cuban believes it's more disruptive than the internet, mobile, or streaming, and how it's already reshaping education, jobs, and entrepreneurship. Cuban shares his views on the broken U.S. healthcare system, his motivations behind launching Cost Plus Drugs, and how GLP-1s might reshape food and wellness. They dive into the changing innovation landscape, the future of hardware and robotics, and why Cuban stepped away from Shark Tank and sold majority control of the Mavericks.