Ep. 30: “Comparative Immunology and Sharks” Featuring Dr. Hanover Matz

Guest:

Dr. Hanover Matz is a Postdoctoral Fellow at the University of Maryland, who recently completed his PhD under the supervision of Dr. Helen Dooley. He discusses why sharks may have evolved adaptive immune systems, the role of T cells, mucosal immunity, and antibodies, and working with sharks in the lab.

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The Immunology Science Round Up

Intestinal Epithelium and Response to Viral Infection – A new study has uncovered a protective role for intraepithelial Ly6A⁺CCR9⁺CD4⁺ T cells against enteric viral infection.

New Mechanism to Activate Cancer-Killing T Cells – Scientists have identified a new mechanism, known as MHC-1 cross-dressing, that is effective in promoting a T cell response.

Long Covid and Breakthrough Infections – Researchers determined that vaccination against SARS-CoV-2 before infection offers partial protection in the post-acute phase of the disease.

Tregs in Traumatic Brain Injury – Targeted delivery of interleukin 2 boosts the number of anti-inflammatory immune cells within the brain to restrict inflammation and damage following injury or stroke.

Image courtesy of Dr. Hanover Matz