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EachPod

Overview of different indirect comparison approaches and methods

Author
Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry
Published
Mon 06 Jan 2020
Episode Link
https://podcastae8fac.podigee.io/102-overview-on-different-indirect-comparison-approaches-and-methods

Click this link to go to the homepage of the post.

We specifically address the following points:

  • Reasons for IC 
  • The classical Bucher approach vs matching adjusted indirect comparisons (MAIC)
  • How to incorporated meta-analyses
  • Different network-meta-analyses approaches (NMA): Bayes vs Frequentist
  • systematic literature reviews (SLR)
  • Cochrane handbook
  • Tools

  • Visualizations
    • Bias 
      • Precision vs bias
      • Pre-specified vs post-hoc
      • Secondary vs primary endpoints
      • Power of IC
      • Publish detailed analyses

        Further references:
        PRISMA http://prisma-statement.org/PRISMAStatement/

        Earlier podcast episode:
        Network meta-analyses: why, what, and how
      • Listen to this episode and know more about Indirect Comparison now!


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