In this episode of AD/PD™ Session Spotlight, we present Plenary Lecture 1 from AD/PD™ 2025, titled "The Alzheimer's Disease Drug Development Pipeline: Observations and Implications," delivered by Dr. Jeffrey Cummings (USA) and chaired by Dr. Cynthia Lemere (USA) and Dr. Henrietta Nielsen (Sweden).
Renowned for his leadership in Alzheimer’s research, Dr. Cummings offers a sweeping and data-driven overview of the evolving landscape of Alzheimer’s drug development—spotlighting trends, challenges, and opportunities shaping the future of treatment.
Key highlights include:
• A record 182 active trials involving 138 unique drug candidates, reflecting unprecedented momentum in the pipeline
• The rising importance of biomarkers across all trial phases, from early discovery to outcome measurement
• A growing focus on inflammation and immunity as therapeutic targets
• Insights into global trial dynamics, including site participation, recruitment hurdles, and regional disparities
• The role of repurposed drugs and innovative trial designs in accelerating progress
• A look ahead at anticipated readouts from ongoing trials, and what they may mean for patients and providers
This episode is highly relevant for drug developers, clinical trial professionals, regulatory stakeholders, and anyone invested in the future of Alzheimer's treatment, offering a clear-eyed perspective on where the field is headed—and why it matters.
This podcast was created using AI to provide a quick and insightful summary of an AD/PD™ 2025 session. While every effort has been made to ensure accuracy, listeners are encouraged to refer to original conference materials and recordings for detailed information.
The AD/PD™ 2025 International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, took place on April 1-5, 2025, in Vienna Austria.
https://adpd.kenes.com/