Ketamine and PTSD Rewiring the Brain

Episode 7 of Talking Ketamine explores the groundbreaking potential of ketamine as a treatment for PTSD. This episode examines a recent study on how a single dose of ketamine, combined with trauma-focused therapy, affects individuals with chronic PTSD. Discover how ketamine may promote flexibility in brain pathways, potentially rewiring the brain’s response to traumatic memories, and explore how these changes might feel for someone undergoing treatment. While highlighting that ketamine treatment for PTSD is still experimental, this offers a hopeful glimpse into the future of mental health treatment and the incredible ability of the brain to heal.

The study in this episode:

Duek, O., Korem, N., Li, Y., Kelmendi, B., Amen, S., Gordon, C., et al. (2023). Long term structural and functional neural changes following a single infusion of Ketamine in PTSD. Neuropsychopharmacology, 48(12), 2056–2066. https://doi.org/10.1038/s41386-023-01606-3

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