New Model to Examine PFAS Sheds Light on Lipid Disruption Mechanisms

Researchers from the Boston University Superfund Research Program Center developed a novel study design that generated new insight on the effects of perfluorooctanoic acid, or PFOA, on cholesterol regulation in the liver. Led by Jennifer Schlezinger, Ph.D., the team also investigated the effects of PFOA on the human peroxisome proliferator activated receptor α, or human PPARα for short, a transcription factor that regulates lipid homeostasis.