Alfred Russel Wallace's 1889 book, Vaccination Proved Useless & Dangerous, challenges the efficacy and safety of vaccination. Wallace presents statistical data from the Registrar-General's reports, arguing that smallpox mortality hasn't significantly decreased despite widespread vaccination. He further contends that vaccination hasn't mitigated smallpox severity and may have even increased other diseases. The book also critiques the reliability of existing vaccination statistics, suggesting biases in data collection and interpretation, and proposes alternative statistical analyses. Accompanying materials include excerpts from a later edition, diagrams illustrating mortality trends, and information about the London Society for the Abolition of Compulsory Vaccination.
https://ia801605.us.archive.org/12/items/b2136140x/b2136140x.pdf