We investigate and help you understand the science behind myostatin inhibition (ACE-083 trial) and berberine supplementation for FSHD; effective in the lab, not so much in you.
- Author
- Peter L Jones, PhD
- Published
- Wed 27 Apr 2022
- Episode Link
- https://podcasters.spotify.com/pod/show/peter-l-jones/episodes/We-investigate-and-help-you-understand-the-science-behind-myostatin-inhibition-ACE-083-trial-and-berberine-supplementation-for-FSHD-effective-in-the-lab--not-so-much-in-you-e1hjqum
Drs. Peter and Takako Jones discuss the ACE-083 trial and the basis of myostatin inhibition for FSHD, and go through the data showing that berberine, despite proof-of-concept studies showing it to be an inhibitor of DUX4 expression, is highly unlikely to be an effective treatment for FSHD.
