#353: Melatonin 101: Antioxidants, Gut Health, Sleep, Skin Protection, and Cancer Research with Nat Niddam
- Author
- Nathalie Niddam
- Published
- Fri 18 Jul 2025
- Episode Link
- https://biohackingsuperhumanperformance.libsyn.com/353-solo
Today, I’m flying solo for a deep—well, more like a just-scratching-the-surface—dive into one of the body’s most fascinating hormones: melatonin. After getting so many of your questions about how melatonin really works, whether it’s just about sleep, and how it might support healthy aging, I decided to tackle all those hot topics head-on in this episode.
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What we discuss:
Why melatonin is complex; plans for future episodes ... 00:00:42
Melatonin as darkness hormone; comparison with vitamin D ... 00:01:51
Top science-backed facts about melatonin ... 00:03:25
Light exposure’s impact and blue light mitigation tips ... 00:05:09
Bioidentical melatonin in plants and animals; supplement notes ... 00:06:41
Production in pineal gland and gut; unique roles ... 00:07:24
Melatonin decline with age and rationale for supplementation ... 00:09:02
Calcified pineal gland and bioregulator benefits ... 00:10:03
Melatonin’s antioxidant, skin, mitochondrial, and anti-cancer effects ... 00:10:37
High-dose melatonin in research and cancer ... 00:12:21
Melatonin from food—phytomelatonin vs. synthetic ... 00:18:37
Supplements: dependency, dosing, and genetic factors ... 00:21:57
Practical tips for dosing and timing ... 00:23:22
Potential drug interactions and safety ... 00:27:38
Wide-ranging health impacts and future research ... 00:28:26
Product recommendations and tracking results ... 00:29:55
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