JACI: In Practice Editor David Khan describes the September issue, the theme of which is “Urticaria and Angioedema”. Theme topics covered include pathogenesis, clinical evaluation, differential diagnosis, and management of chronic urticaria with or without angioedema. Dr. Khan then presents the Highlights of the Original Articles in the issue, which are on the topics of Urticaria and Angioedema, Asthma, Drug Allergy, Food Allergy, Inborn Errors of Immunity, and Rhinitis.