In this episode, we review post-heart transplant issues, including immunosuppression, rejection, complications, and long-term monitoring. What are the three phases of immunosuppression? How do calcineurin inhibitors, antimetabolites, and corticosteroids prevent rejection? What are the key differences between hyperacute rejection, acute cellular rejection, antibody-mediated rejection, and chronic rejection? At what frequency should heart transplant recipients undergo surveillance for coronary allograft vasculopathy? What factors increase the risk of post-transplant malignancy and infection? Why do heart transplant patients have a higher resting heart rate, and how does this affect their exercise capacity? Tune in for answers to these questions.
Difficulty Level: Intermediate
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