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IBS news flash. See the mechanisms behind IBS and functional constipation pain.

Author
Heather Van Vorous
Published
Thu 27 Mar 2025
Episode Link
https://heathervanvorous.substack.com/p/ibs-news-flash-see-the-mechanisms-d73

IBS news flash. See the mechanisms behind IBS and functional constipation pain.

Many pathways with multiple factors add to abdominal pain in chronic constipation

A fascinating new research abstract just came out on decoding abdominal pain in constipation-predominant Irritable Bowel Syndrome and functional constipation.

It’s focused on the mechanisms underlying the pain.

In plain English:

There are many pathways with multiple factors that add to abdominal pain in chronic constipation.

1. Genetics

2. Stress

3. Diet

4. Sex differences and hormones make things worse for women

5. Nervous system alterations outside the gut affect pain

6. Serotonin metabolism in the gut affects pain threshold and bowel motility

7. Gut bacteria imbalances add to bowel sensitivity and motility

8. Restricted bowel movements, pain, and bloating/distention affect each other via accumulated feces and gas. This causes a cycle of gut discomfort.

9. All of the pathways listed above are interconnected

10. Whew!

And more about IBS constipation

You are not alone.

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P.S. If you have any questions or comments I'd love to hear them - just reply to this email to reach me directly. I am overwhelmed with emails but I try to answer everyone. If you need immediate help please join my private IBS coaching.

XOXO

Heather

Heather Van Vorous Over 40 years dealing with IBSGet full help for IBS here



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