Tremella Mushroom hydrates the skin, supports immune health and increases anti-oxidants. Interview with Mark J. Kaylor We have used Mushroom Wisdom products in my family on and off for many years. I remember when Maitake Products D-Fraction was introduced as a potent immune supplement. It was the first mushroom product that I learned about that had clinical science. Maitake-D Fraction set a standard in my mind that persists to this day. I expect that companies that make claims for their products should have science and research to verify the claimed benefits. They should also be transparent and honest with their customers.