The Problem of Cell Senescence – Episode 27

On this episode, Dr. Gladden, Mark and Robb discuss the problem of senescent cells in the body. Senescent cells stop dividing, but they don’t die off through apoptosis. Rather than making way for new cells, they can become dysfunctional, release toxins and can contribute to aging and disease. 

Robb shares a study on senolytic drugs, which helps induce the death of senescent cells, showing promise so far in helping mice live longer.

They discuss some habits that can help maintain telomere length to prolong the longevity of cells. They also cover some of the treatments that the medical community is exploring to deal with senescent cells.

They talk about how stress helps the body stay healthier and that balance in your body and vigilance in healthy habits are needed to promote longevity.