Don and Ben are joined by surprise guest Paul Breslin from Rutgers. Paul is a geneticist who works in the area of taste and when he heard that Don had a podcast he had to be on it. After Don plays his favorite, but Ben's least favorite game of "guess the guest," where Ben almost got there, they start in on food, food chemistry, genetics and evolution. The guys talk about the ubiquity of fermentation in human foods, cooking, why foods taste the way they do, the evolution of taste receptors. They also get into questions like what does eating pure DNA or RNA taste like. They talk about hot foods/spices, electronic noses for pathogens and spoilage and some other stuff.