📝 "What Are Key Features Of The Adenomatoid Odontogenic Tumor?"

Quick Review #276 - #pathology #oralpathology #doctorgallagher #oralsurgery #oralsurgeon #dentist #dentistry #dental #aot #adenomatoidodontogenictumor

- 4.13.25

Adenomatoid Odontogenic Tumor (AOT) is a benign (hamartomatous) epithelial odontogenic tumor most commonly affecting adolescents and young adults, with a strong predilection for females (2:1) and typically occurring during the second decade of life. It accounts for 3–7% of all odontogenic tumors.

Location:

- Maxillary anterior region is most frequently involved (up to 65% of cases).

- Often associated with an impacted tooth, especially the maxillary canine.

Clinical Presentation:

- Usually asymptomatic, slow-growing lesion.

- May present with painless swelling or delayed tooth eruption.

Radiographic Features:

- Appears as a well-circumscribed unilocular radiolucency.

- Frequently surrounds the crown and may extend apically beyond the CEJ, unlike a dentigerous cyst.

- Characteristic presence of fine, “snowflake”-like calcifications within the radiolucency in 70% of cases.

- Often causes mild expansion but rarely leads to root resorption.

Histopathology:

- Composed of spindle-shaped epithelial cells forming duct-like structures, rosettes, and whorled patterns.

- May contain eosinophilic amyloid-like material and dystrophic calcifications.

- The name “adenomatoid” reflects the duct-like structures microscopically, though no glandular differentiation is present.

Variants:

- Follicular type: associated with an impacted tooth.

- Extrafollicular type: not associated with a tooth but still intraosseous.

- Peripheral type: rare, presents in gingiva.

Treatment and Prognosis:

- Managed by simple enucleation.

- Excellent prognosis with rare recurrence due to its encapsulated nature.

Key Differentiators:

- More common in younger females, anterior maxilla, and often misdiagnosed as a dentigerous cyst or calcifying odontogenic cyst.

- Radiographic extension beyond the CEJ and presence of intra-lesional calcifications help distinguish it from other cystic lesions.

References:

1. Loganathan, K., & Vaithilingam, B. (2014). Adenomatoid odontogenic tumor in the mandible: A case report. International Journal of Dental Sciences and Research, 2(4B), 6–8.

2. Neville, B. W., Damm, D. D., Allen, C. M., & Chi, A. C. (2015). Oral and Maxillofacial Pathology (4th ed.). Saunders.

3. Philipsen, H. P., & Reichart, P. A. (1998). Adenomatoid odontogenic tumour: Facts and figures. Oral Oncology, 34(5), 389–399.

4. Buchner, A., Merrell, P. W., & Carpenter, W. M. (2006). Relative frequency of central odontogenic tumors: A study of 1,088 cases from Northern California and comparison to studies from other parts of the world. Journal of Oral and Maxillofacial Surgery, 64(9), 1343–1352.

5. ChatGPT. 2025.

#podcast #dentalpodcast #doctorgallagherpodcast #doctorgallagherspodcast #doctor #dentist #dentistry #oralsurgery #dental #dentalschool #dentalstudent #doctorlife #dentistlife #oralsurgeon #doctorgallagher