Insider Look at Rabacfosadine (Tanovea) from Shelved Human Drug to Dog Lymphoma Treatment | Dr. Doug Thamm #284

Dr. Doug Thamm discusses the development and use of Tanovea, a drug for treating lymphoma in dogs. He explains the drug's origins, initially researched as a human cancer therapeutic in collaboration with Gilead Sciences, and its transition to veterinary use.  
Dr. Thamm provides insights into Tanovea’s application, dosage, and effectiveness compared to the CHOP protocol, as well as its potential side effects and other possible uses in different cancer types like multiple myeloma. The episode also delves into related immunotherapy research and personal reflections from Dr. Thamm, a double cancer survivor, on his career choice in veterinary oncology.

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Related Videos: 
https://www.youtube.com/watch?v=G0iRyKshzq8 

Related Links: 
Our article on lymphoma: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/ 
Our article on Tanovea: https://www.dogcancer.com/articles/drugs/tanovea-rabacfosadine-chemotherapy/ 
Get the facts on dog cancer remission: https://www.dogcancer.com/articles/stats-and-facts/dog-cancer-remission/ 

Chapters: 
00:00 Introduction 
00:13 Interview with Dr. Doug Thamm 
00:26 The Early Involvement with Tanovea 
00:41 Challenges and Discoveries in Drug Development 
02:16 Transition from Human to Veterinary Use 
02:48 Clinical Trials and Dosage Experiments 
06:45 FDA Approval and Practical Use 
08:05 Comparing Tanovea and CHOP Protocol 
15:23 Exploring Alternative Treatments: Laverdia 
18:43 Off-Label Uses and Future Research 
23:46 Exploring Tanovea's Effectiveness in Blood Cancers 
25:14 Cost Comparison: Tanovea vs. CHOP 
26:15 Side Effects of Tanovea 
28:47 Pulmonary Fibrosis and Breed-Specific Risks 
32:52 Personal Cancer Journeys: Dr. Doug and His Wife 
38:23 Debunking Myths About Dog Cancer Treatment 
42:24 The Future of Cancer Treatment: Immunotherapy 
45:23 Conclusion and Resources 
 
Get to know Dr. Doug Thamm:
https://www.dogcancer.com/people/doug-Thammm-v-m-d-diplomate-acvim-oncology/  
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/  
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