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A Daily Pill for Dog Lymphoma? The Promise of Monepantel Explained | Kim Agnew, BVSc #287

Author
Dog Podcast Network
Published
Mon 07 Jul 2025
Episode Link
https://www.dogcancer.com/podcast/

Originally aired in 2023, Molly Jacobson interviews Dr. Kim Agnew about the groundbreaking trials of Monepantel, a sheep dewormer repurposed as a potential treatment for canine lymphoma. Discover the science behind this innovative therapy, its potential to stabilize lymphoma, and how it compares to traditional treatments like chemotherapy and prednisone. 

Key Topics: 

What is Monepantel, and how was it discovered? 

The mechanism behind Monepantel's ability to target cancer cells. 

Early trial results: Quality of life and stability for dogs with B-cell lymphoma. 

How Monepantel compares to prednisone and chemotherapy. 

Insights into ongoing and future clinical trials. 

How dog lovers can participate in studies. 

Your Voice Matters!  
If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.  

Related Videos: 
https://www.youtube.com/watch?v=_92w6TTXM5c  
https://www.youtube.com/watch?v=uAZrPM1X8ww  

Related Links: 
PharmAust Dog Lymphoma Clinical Trial: https://www.pharmaust.com/petdogtrial/ 

Chapters: 
00:00 Introduction 
00:30 Meet Dr. Kim Agnew and Monepantel Overview 
01:15 The Origin of Monepantel: From Dewormer to Cancer Fighter 
03:30 How Monepantel Targets Cancer Cells 
07:00 Insights on Clinical Trials for Canine Lymphoma 
09:30 Benefits of Monepantel: A Daily Pill for Dogs 
12:00 Comparing Monepantel to Chemotherapy and Prednisone 
14:45 Early Trial Results: Stabilizing Lymphoma in Dogs 
18:30 Why Lymphoma Was Chosen for Trials 
20:00 Potential for Treating Other Cancers in Dogs 
23:15 How to Enroll Dogs in Clinical Trials 
26:45 Side Effects and Safety of Monepantel 
31:00 Future Trials and Research Goals 
34:30 Closing Thoughts and Resources 
33:55 Closing Remarks and Resources 
 
Get to know Kim Agnew, BVSc:
https://www.dogcancer.com/people/kim-agnew-bvsc/    
For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/  
Learn more about your ad choices. Visit megaphone.fm/adchoices

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