Dr Kamar Ameen-Ali - The importance of including both sexes in preclinical dementia research

Dr Kamar Ameen-Ali narrates her blog written for Dementia Researcher.

In biomedical research there has historically been a tendency towards sole inclusion of males, particularly in preclinical animal studies. The reason has often centred on the potential variability of females relating to fluctuations in hormones which could confound the data. But could this bias towards studying males account for poor translation of preclinical to clinical research? In this blog Kamar discusses the importance of including both sexes in preclinical research, and why this might significantly advance progress in dementia research.

Find the original text, and narration here on our website.

https://www.dementiaresearcher.nihr.ac.uk/guest-blog-the-importance-of-including-both-sexes-in-preclinical-dementia-research/

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Dr Kamar Ameen-Ali is a Lecturer in Biomedical Science at Teesside University & Affiliate Researcher at Glasgow University. In addition to teaching, Kamar is exploring how neuroinflammation following traumatic brain injury contributes to the progression of neurodegenerative diseases that lead to dementia. Having first pursued a career as an NHS Psychologist, Kamar went back to University in Durham to look at rodent behavioural tasks to completed her PhD, and then worked as a regional Programme Manager for NC3Rs.

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This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support.