Cure HSPB8 - The Podcast
Welcome to the Cure HSPB8 Podcast, a series dedicated to raising awareness and sharing critical information about HSPB8 Myopathy. This podcast is designed for individuals and families affected by this rare neuromuscular condition, as well as clinicians and researchers working to make a difference.
In each episode, we focus on one key topic related to HSPB8 Myopathy — whether it’s the latest advancements in research, genetic testing, diagnosis, management strategies, or insights from the rare disease space. We’ll discuss recent publications, dive deep into important clinical topics, and explore the latest findings in the field. Episodes will sometimes feature journal club discussions, where we summarize and analyze key publications in the HSPB8 space, helping to make complex research more accessible.
Our goal is to inform, connect, and empower the HSPB8 community, while providing resources that will support families, clinicians, and researchers alike. Together, we can build a stronger, more informed community as we work towards a life free from HSPB8 Myopathy.
This podcast is generated with the support of AI, NotebookLM. We do everything in our power to ensure accuracy and clarity, but we welcome your feedback. If you spot anything that needs correction or want to contribute, please reach out to us at [email protected].
- Update frequency
- every 20 days
- Average duration
- 14 minutes
- Episodes
- 7
- Years Active
- 2025
EP 7: Tedesco et al. 2025: How New Frameshifts Change HSPB8 Disease
In this episode, we look at the 2025 study by Tedesco et al., “Novel HSPB8 mutations in severe early-onset myopathy with involvement of respiratory and cardiac muscles cause proteostasis defects in c…
EP 6: Advanced (for researchers): What is HSPB8 Myopathy, or Myofibrillar Myopathy type 13 (MFM13) with rimmed vacuoles?
Episode 6 - What is Myofibrillar Myopathy type 13 (MFM13) with rimmed vacuoles?
In this episode, we take a deep dive into the molecular mechanisms behind Myofibrillar Myopathy type 13 (MFM13) with Rim…
EP 5: Journal Club: HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies
Episode 5 – Tedesco et al. 2023: Molecular Insights into HSPB8
In this episode, we dive into the 2023 study by Tedesco et al., titled "HSPB8 frameshift mutant aggregates weaken chaperone-assisted sele…
EP 4: When to suspect HSPB8 Myopathy (MFM13)? Intro for clinicians
In this episode, we explore the key clinical features of HSPB8 Myopathy - an ultra-rare, autosomal dominant, progressive muscle-wasting condition. With fewer than 30 documented cases, awareness among…
EP 3: Journal club: The Spectrum of Small Heat Shock Protein B8 (HSPB8) - Associated Neuromuscular Disorders
How can a small heat shock protein cause big problems in muscle and nerve cells?
This episode explores HSPB8, a key player in chaperone-assisted selective autophagy (CASA), which helps clear misfolde…
EP 2: For beginners - Introduction to HSPB8 Myopathy or Myofibrillar Myopathy type 13 (MFM13) with Rimmed Vacuoles: What You Need to Know
Episode 2 – Introduction to HSPB8 Myopathy: What You Need to Know
In this episode, we break down HSPB8 Myopathy, a rare genetic condition that causes progressive muscle weakness and degeneration. We’l…
EP 1: Intro to Cure HSPB8: Why we’re here and where we’re going
Episode 1 – Our Mission, Our Vision, Our Voice
Welcome to the Cure HSPB8 Podcast. In this inaugural episode, we share how and why Cure HSPB8 came to be — and what drives our mission to improve the liv…