BiotecInsights

This study validates a rapid affinity chromatography method for quantifying immunoglobulin G from human plasma. Utilizing POROS CaptureSelect FcXP resin, it achieves a 2.5-minute cycle time, excellen…

This study investigates pH-dependent flocculation in Komagataella phaffii. We found it peaks at pH 4.0 and is reversible. Flo5-1 critically affects this process, and Nrg1 negatively regulates it. Our…

This is an interview-style podcast discussing a recently published paper on the characterization of the MapADO enzyme. The conversation is between an interviewer and an expert, covering the enzyme's …

Cultivated meat's future hinges on affordable, sustainable cell culture media. This review details serum-free strategies, including novel ingredients and circular systems, to overcome cost and regula…

New research from acib, Graz University of Technology, and myBIOS GmbH systematically compares ethanol- and methanol-inducible promoters in Komagataella phaffii, revealing insights into constitutive …

This podcast explores the current challenges of AI in biomolecular structure prediction, specifically concerning stereochemistry and chiral molecules. We discuss the necessity of human oversight, col…

Discover how a new stepwise gene activation strategy allows cell factories to adapt and achieve significantly higher therapeutic protein production compared to traditional methods. This innovation pr…

Researchers have found inexpensive, food-grade alternatives to expensive serum albumins in cell culture media, potentially cutting costs for cultivated meat production and biopharmaceuticals by up to…

A meta-analysis reveals the core genetic blueprint and dynamic gene regulation of CHO cell factories.

This podcast details the engineering of transmembrane alkane monooxygenases (AlkB) to improve Tulipalin A synthesis. The research focuses on enhancing the hydroxylation of isoprenyl acetate, a crucia…

Dive deep into the complex world of Adeno-Associated Virus (AAV) purification for gene therapy. Our expert guest explains the challenges of separating perfect therapeutic AAVs from a myriad of impuri…

 Discover how scientists harnessed a unique bacterial lipase, SpL, featuring a novel catalytic tetrad and dual access tunnels, to achieve highly efficient synthesis of pharmaceutical-relevant amides …

This interview explores the systematic immobilization of L-lactate oxidase on various porous carriers, revealing that hydrophilic agarose supports with amine groups yield the highest activity. Key di…

Explore the innovative research from acib GmbH on using NADH-driven enzymes for the sustainable reduction of carboxylic acids into valuable aldehydes and alcohols. Learn about the potential of this b…

Explore a breakthrough in biocatalysis: a highly efficient, one-pot enzyme cascade synthesizes pseudouridine-5'-phosphate and related C-nucleosides from simple sugars and nucleobases. Discover how pr…