The Interferon I role in autoimmune disease and the corruption of mechanisms that lead to age-related morbidity and mortality.DJGPhD. 22.9.21
- Author
- Dr Daniel J. Guerra
- Published
- Wed 22 Sep 2021
- Episode Link
- https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/episodes/The-Interferon-I-role-in-autoimmune-disease-and-the-corruption-of-mechanisms-that-lead-to-age-related-morbidity-and-mortality-DJGPhD--22-9-21-e17odsn
Interferons are innate immune agents of inflammation and recovery. Mutations or epigenetic modifications associated with advanced aging may corrupt interferon pathway fidelity involving mitophagy leading to autoimmune disease and morbidity later in life.
References
Nat Immunol. 2021 Mar; 22(3): 312–321
J Neuroinflammation. 2019; 16: 236.
