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The Association of NAD+, Melatonin, &Sirtuins via DNA Damage Repair and Epigentic Chromatin Remodeling with Immunosenescence is evident

Author
Dr Daniel J. Guerra
Published
Wed 21 Oct 2020
Episode Link
https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/episodes/The-Association-of-NAD--Melatonin--Sirtuins-via-DNA-Damage-Repair-and-Epigentic-Chromatin-Remodeling-with-Immunosenescence-is-evident-eld1ok

This episode lays the foundation for a common precursor-the essential amino acid L-tryptophan, of both melatonin and NAD+ and the PARP mediated DNA repair pathways linked to tumorigenesis  on one hand and in DNA Damage repair-linked cessation of apoptosis on the other, in the aging  human Central Nervous System.


Cells. 2019 Sep; 8(9): 1047.


Int J Alzheimers Dis. 2011: 741974.

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