Hepatocellular Carcinoma Pathobiochemistry Chapter/Lecture V from Dr. Daniel J. Guerra. Authentic Biochemistry.28 May 2019.

In this segment I provide more discussion of the published evidence linking glycolytic pathway enzymes to HCC progression. The expression of certain interfering RNA's that differentially regulate gene expression and promoter habilitation can lead to cyclin dependent kinase mediated chromatin remodeling enhancing cell -specific expression of enzyme isoforms that promote rather than defeat disease progression.