Dr Guerra examines proteases and protease inhibitors in ovarian and hepatocellular cancers and their pathobiochemical mechanisms. 03 July 2020.
- Author
- Dr Daniel J. Guerra
- Published
- Fri 03 Jul 2020
- Episode Link
- https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/episodes/Dr-Guerra-examines-proteases-and-protease-inhibitors-in-ovarian-and-hepatocellular-cancers-and-their-pathobiochemical-mechanisms--03-July-2020-eg92nr
Dr Guerra presents how a protease inhibitor protects a serine protease that is linked to ovarian cancer progression plus how protease inhibitor polymerization overloads the Endoplasmic Reticulum Associated Degradation pathway and Unfolded Protein Response to induce autophagy-linked Hepatocellular Carcinoma. Finally, a mechanistic step-wise summary of the serine protease catalytic triad is presented. Published 03 July 2020.
