TRAUMA ANESTHESIA SERIES (PART 3): BLOOD PRODUCTS, VASOPRESSORS & MASSIVE TRANSFUSION | EP47

In part 3 of the Trauma and Burn Anesthesia series, we focus on blood product administration and fluid resuscitation, exploring how transfusions are tailored to support oxygen delivery, coagulation, and hemodynamic stability in critically injured patients. The episode examines the indications and composition of packed red blood cells, platelets, plasma, and cryoprecipitate, as well as the role of crystalloids and colloids in resuscitation. Key complications of transfusion—including transfusion related acute lung injury (TRALI) and transfusion associated circulatory overload (TACO)—are highlighted with emphasis on recognition, prevention, and management. Listeners are also guided through the principles of massive transfusion protocols (MTPs), including balanced product ratios, calcium supplementation, and rapid delivery systems that optimize outcomes in life-threatening hemorrhage.

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