The Clock Within Us Ezra Wade introduces the biological mechanisms that drive aging at the cellular level. The episode explores telomeres—the protective caps on chromosomes that shorten with each cell division—and explains how cellular damage accumulates through oxidative stress, DNA damage, and declining repair systems. Wade examines senescent cells, those damaged cells that stop dividing but continue secreting harmful compounds, and explains why aging isn't simply about time passing but about multiple biological systems breaking down in interconnected ways. The episode establishes the scientific foundation for understanding aging as a modifiable biological process rather than an inevitable decline.
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